Eylea 40 mg/mL solution for injection in pre-filled syringe
Sponsors
Abbvie Deutschland GmbH & Co. KG, Centre Hospitalier Universitaire De Dijon, Opthea Limited, Centre Hospitalier Universitaire De Nice, Medical University Of Graz, Medical University Of Graz
Conditions
Diabetic Macular Edema (DME)Macular neovascularization secondary to age-related macular degeneration (nAMD)Neovascular Age-related Macular Degeneration (wet AMD)Neovascular age-related macular degenerationPatient with large choroid melanoma 7 mm thick and/or more than 15 mm of basal diameter treated by proton therapycentral retinal vein occlusionsmacular telangiectasia type 1
Phase 2
Phase 3
A Randomized, Partially Masked, Controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants with nAMD (ASCENT)
Active, not recruitingCTIS2023-503666-23-00
Start: 2024-06-07Target: 216Updated: 2025-08-20
TELeMAC - Comparative multicenter randomized study of aflibercept versus placebo in macular telangiectasia type 1
CompletedCTIS2024-511885-35-00
Start: 2019-07-03End: 2025-03-26Target: 46Updated: 2025-07-24
A Phase 3, Multicentre, Double-masked, Randomised Study to Evaluate the Efficacy and Safety of Intravitreal OPT-302 in Combination with Aflibercept, Compared with Aflibercept Alone, in Participants with Neovascular Age-related Macular Degeneration (nAMD)
CompletedCTIS2024-512880-30-00
Start: 2021-08-27End: 2025-03-31Target: 475Updated: 2025-04-23
Neovascular glaucoma prevention by intravitreal injections of anti-VEGF in patients treated by protontherapy in case of large choroid melanoma
CompletedCTIS2024-513746-11-00
Start: 2017-06-08End: 2025-01-31Target: 56Updated: 2024-12-19
Faricimab for high-frequent Aflibercept treated Neovascular age-related macular degeneration: a monocenter, randomized, double-masked comparator-controlled study (FAN study)
CompletedCTIS2024-515377-10-00
Start: 2023-06-12End: 2025-02-26Target: 70Updated: 2024-11-18
A Phase 3, Randomized, Double-Masked, Active-Controlled Trial of a Single Intravitreal Injection of 4D-150 in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration (4FRONT-2)
RecruitingCTIS2025-521349-25-00
Start: 2025-12-09Target: 298Updated: 2025-12-19
A Phase 3, Multicenter, Prospective, Randomized, Double-Masked, Parallel-Group Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept (2 mg) in Participants with Diabetic Macular Edema (DME) (EYP-1901-304)
Not yet recruitingCTIS2025-523938-10-00
Target: 40Updated: 2026-03-30