EYE103
Sponsors
Eyebiotech Limited, Eyebiotech Limited, Eyebiotech Limited, EyeBiotech Ltd.
Conditions
Branch Retinal Vein Occlusion (BRVO)Diabetic Macular EdemaDiabetic Macular Edema (DME)Neovascular Age-Related Macular Degeneration (NVAMD)Neovascular Age-related Macular Degeneration (NVAMD)
Phase 1
Phase 2
A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME
Active, not recruitingNCT06571045
Start: 2024-08-07End: 2027-12-31Updated: 2026-08-20
A RANDOMIZED, DOUBLE-MASKED, MULTI-CENTER, 3-ARM PHASE 2/3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF INTRAVITREAL EYE103 COMPARED WITH INTRAVITREAL RANIBIZUMAB (0.5MG) IN PARTICIPANTS WITH DIABETIC MACULAR EDEMA
Active, not recruitingCTIS2024-510944-30-00
Start: 2024-11-22Target: 585Updated: 2026-01-19
A Study of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME
Active, not recruitingNCT06957080
Start: 2025-04-16End: 2028-03-30Updated: 2026-08-20
A Randomized, Double-masked, Multi-center, 3-Arm Pivotal Phase 2/3 Study to Evaluate the Efficacy and Safety of Intravitreal EYE103 Compared with Intravitreal ranibizumab (0.5mg) in Participants with Diabetic Macular Edema
Active, not recruitingCTIS2025-520809-12-00
Start: 2025-10-16Target: 465Updated: 2025-11-19
A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO
RecruitingNCT07205887
Start: 2025-09-12End: 2028-06-30Target: 160Updated: 2026-09-04