Eye Drops Suspension
Sponsors
AbbVie Deutschland GmbH & Co. KG, Immunogen Inc.
Conditions
Platinum-Resistant Advanced High-Grade Epithelial OvarianPlatinum-sensitive epithelial ovarianPrimary PeritonealRecurrent Ovarian Cancer with High Folate Receptor-Alpha ExpressionRecurrent endometrial cancerand primary peritoneal cancer (EOC)epithelial ovarianfallopian tube
Phase 1
Phase 2
Multicenter, open-label, phase 2 study of carboplatin plus mirvetuximab soravtansine followed by mirvetuximab soravtansine continuation in folate receptor-alpha positive, recurrent platinum sensitive, high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancer following 1 prior line of platinum-based chemotherapy
RecruitingCTIS2022-501220-14-00
Start: 2023-10-17Target: 45Updated: 2025-12-10
A Randomized Phase 2 Study of Ocular Toxicity Evaluation and Mitigation During Treatment with Mirvetuximab Soravtansine in Patients with Recurrent Ovarian Cancer with High Folate Receptor-Alpha Expression
Active, not recruitingCTIS2023-505617-24-00
Start: 2024-11-05Target: 46Updated: 2025-12-15
Phase 3
2022-501606-35-00 – Randomized, multicenter, open-label, Phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FRα-high recurrent platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers who have not progressed after second-line platinum-based chemotherapy plus bevacizumab (GLORIOSA).
RecruitingCTIS2022-501606-35-01
Start: 2024-02-21Target: 110Updated: 2026-01-21
MIRASOL: A Randomized, Open-label, Phase 3 Study of Mirvetuximab Soravtansine vs. Investigator’s Choice of Chemotherapy in Platinum- Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression
CompletedCTIS2024-516111-25-00
Start: 2020-11-09End: 2024-10-29Target: 1Updated: 2024-10-15