Experimental group:This arm uses transapical beating-heart septal myectomy procedure for septal reduction in patients with obstructive hypertrophic cardiomyopathy. The procedure is performed via a lef

3 trials

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Beijing Anzhen Hospital, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Beijing Anzhen Hospital

Conditions

Obstructive Hypertrophic Cardiomyopathy

Unknown Phase

Transapical Beating-Heart Septal Myectomy Using Beating-Heart Myectomy Device Versus Transaortic Septal Myectomy in Patients With Obstructive Hypertrophic Cardiomyopathy: A Multicenter Randomized Controlled Trial

RecruitingChiCTR2400087414

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Beijing Anzhen HospitalObstructive Hypertrophic Cardiomyopathy

Start: 2024-08-02Updated: 2025-05-26

Comparative Evaluation of the Safety and Efficacy of Transapical Beating-Heart Septal Myectomy versus Mavacamten (CAMZYOS®) in the Treatment of Obstructive Hypertrophic Cardiomyopathy: A Prospective, Multicenter, Randomized Controlled, Superiority Clinical Trial

Active, not recruitingChiCTR2500114043

Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyObstructive Hypertrophic Cardiomyopathy

Start: 2025-12-15Updated: 2026-05-04

Transapical Beating-Heart Septal Myectomy Using a Beating-Heart Myectomy Device in Patients With Obstructive Hypertrophic Cardiomyopathy: A Prospective Multicenter Single-Arm Study

Active, not recruitingChiCTR2500114575

Beijing Anzhen HospitalObstructive Hypertrophic Cardiomyopathy

Start: 2025-12-15Updated: 2026-01-05