Experimental group:TAN-118 Tablets

4 trials

Sponsors

Nanjing First Hospital, Sir Run Run Shaw Hospital, Affiliated to Zhejiang University School of Medicine

Conditions

InflammatoryBowelDisease,IBD

Phase 1

To evaluate the safety and tolerability of TAN-118 tablets in healthy adult subjects

Active, not recruitingChiCTR2500102120

Nanjing First HospitalInflammatoryBowelDisease,IBD

Start: 2025-05-16Updated: 2025-05-12

Phase I clinical trial to evaluate the local pharmacokinetics of TAN-118 tablets in healthy adult subjects

Active, not recruitingChiCTR2600120509

Nanjing First HospitalInflammatoryBowelDisease,IBD

Start: 2026-03-16Updated: 2026-03-23

Phase 2

A randomized, double-blind, placebo-controlled Phase IIa exploratory proof-of-concept (PoC) clinical trial to evaluate the safety, tolerability, preliminary efficacy and pharmacokinetics of TAN-118 tablets in patients with active ulcerative colitis.

Active, not recruitingChiCTR2600124718

Sir Run Run Shaw Hospital, Affiliated to Zhejiang University School of MedicineInflammatoryBowelDisease,IBD

Start: 2026-05-15Updated: 2026-05-18

A multicenter, randomized, double-blind, placebo-controlled Phase II clinical trial evaluating the efficacy, safety, and pharmacokinetic/pharmacodynamic characteristics of TAN-118 tablets in adult patients with moderate to severe active ulcerative colitis.

Active, not recruitingChiCTR2600125341

Sir Run Run Shaw Hospital, Affiliated to Zhejiang University School of MedicineInflammatoryBowelDisease,IBD

Start: 2026-08-10Updated: 2026-08-10