experimental group:CAR-T cell

5 trials

Sponsors

Tianjin First Central Hospital, The First Bethune Hospital of Jilin University, Shaanxi Provincial People's Hospital

Conditions

Acute myeloid leukemiaColorectal cancer, gastric cancer, liver cancer, pancreatic cancer, esophageal adenocarcinoma, esophagogastric junction cancer, etc.Hematological malignanciesOvarian cancer, melanoma, pancreatic cancer, gastric cancer, etc.Refractory or relapsed B-cell lymphoma

Early Phase 1

CAR-T cells in the treatment of relapsed and refractory hematological malignancies

RecruitingChiCTR2000041025

Tianjin First Central HospitalHematological malignancies

Start: 2020-12-31Updated: 2021-03-01

The clinical study of CAR-T cells in the treatment of acute myeloid leukemia

RecruitingChiCTR2000041054

Tianjin First Central HospitalAcute myeloid leukemia

Start: 2020-12-31Updated: 2021-03-01

Clinical study on the safety and effectiveness of CAR-T cells in the treatment of advanced GUCY2C-positive digestive system tumors

RecruitingChiCTR2100053828

The First Bethune Hospital of Jilin UniversityColorectal cancer, gastric cancer, liver cancer, pancreatic cancer, esophageal adenocarcinoma, esophagogastric junction cancer, etc.

Start: 2021-11-15Updated: 2022-10-24

Clinical study on the safety and effectiveness of CART cells in the treatment of advanced ALPP-positive tumors

RecruitingChiCTR2100053829

The First Bethune Hospital of Jilin UniversityOvarian cancer, melanoma, pancreatic cancer, gastric cancer, etc.

Start: 2021-11-15Updated: 2022-10-24

Unknown Phase

Chimeric antigen receptor T cells (CAR-T) in the treatment of refractory/relapsed B-cell lymphoma

Active, not recruitingChiCTR2200060553

Shaanxi Provincial People's HospitalRefractory or relapsed B-cell lymphoma

Start: 2022-05-30Updated: 2024-05-27

Related Papers

Efficacy analysis of CAR-T cells against CD123-positive malignant tumors and exploration of the feasibility of combination therapy with venetoclax.

2026-06-11

Updated data of CLL1 CAR-T cell therapy in adult patients with relapsed/refractory acute myeloid leukemia.

2025-12-18

Infectious complications distribution following CLL1 CAR-T cell therapy for acute myeloid leukemiass

Cancer Immunology Immunotherapy2025-03-152 citations

Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation

Frontiers in Immunology2025-01-173 citations

Efficacy and Safety of CAR-T Therapy Targeting CLL1 in Patients with Extramedullary Diseases of Acute Myeloid Leukemia

Blood2024-11-051 citations

A Phase I Clinical Trial of CLL-1 CAR-T Cells for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia in Adults

Blood2023-11-0220 citations

A phase 1 dose-escalation study of GCC19 CART a novel coupled CAR therapy for subjects with metastatic colorectal cancer.

Journal of Clinical Oncology2022-06-015 citations