Exendin (9-39)

DRUG8 trials

Conditions

Congenital HyperinsulinismDiabetesGlucose Metabolism DisordersHyperinsulinemia HypoglycemiaHypoglycemiaInsulin SecretionObesityPreDiabetes

Phase 1

Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia

TerminatedNCT00835328

Diva De LeonCongenital Hyperinsulinism

Start: 2009-08-26End: 2017-01-28Updated: 2020-06-01

Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery

TerminatedNCT02550145

Tracey McLaughlinHypoglycemia

Start: 2014-02-28Updated: 2024-12-04

Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia

CompletedNCT02996812

Tracey McLaughlinHyperinsulinemia Hypoglycemia

Start: 2015-04-30End: 2016-08-31Updated: 2024-12-04

Phase 4

Regulation of Insulin Secretion by the GLP-1 Receptor

TerminatedNCT02844907

VA Office of Research and DevelopmentInsulin Secretion

Start: 2018-07-01End: 2021-12-31Updated: 2024-12-12

Cardiovascular Effects of GLP-1 Receptor Activation

CompletedNCT03101930

Vanderbilt University Medical CenterObesity, PreDiabetes

Start: 2017-05-01End: 2021-06-24Updated: 2022-10-18

Unknown Phase

Ghrelin Effect on Beta Cell Function in Health and Disease

NCT01729299

David DalessioDiabetes

Start: 2013-04-30End: 2014-04-30Target: 30Updated: 2013-04-04

Delineation of the Role of Glucagon-like Peptide-1 Signalling in Relation to Increased Carbohydrate Content in the Distal Small Intestines

CompletedNCT03241303

University Hospital, Gentofte, CopenhagenGlucose Metabolism Disorders

Start: 2017-08-01End: 2018-01-01Updated: 2020-03-26

The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D

CompletedNCT03246451

University Hospital, Gentofte, CopenhagenGlucose Metabolism Disorders

Start: 2017-07-01End: 2017-12-10Updated: 2018-07-09

Related Papers

The role of glucagon-like peptide 1 in the postprandial effects of metformin in type 2 diabetes: a randomized crossover trial

European Journal of Endocrinology2024-07-255 citations

Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia.