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Etrolizumab

DRUG13 trials

Sponsors

Genentech, Inc., Hoffmann-La Roche

Conditions

Colitis, UlcerativeCrohn DiseaseCrohn's DiseaseCrohn's disease inflammatory bowel diseaseHealthy VolunteerHealthy VolunteersUlcerative Colitischronic bowel inflamation inflammatory bowel disease

Phase 1

Phase 2

Phase 3

Study for Participants With Ulcerative Colitis Previously Enrolled in Etrolizumab Phase II/III Studies
TerminatedNCT02118584
Hoffmann-La RocheUlcerative Colitis
Start: 2014-09-15End: 2023-10-05Updated: 2024-10-23
A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumor Necrosis Factor (TNF) Inhibitors
CompletedNCT02136069
Hoffmann-La RocheUlcerative Colitis
Start: 2014-12-24End: 2020-06-23Updated: 2021-12-03
A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors
CompletedNCT02163759
Hoffmann-La RocheUlcerative Colitis
Start: 2014-11-04End: 2020-03-19Updated: 2021-07-23
A Study of the Efficacy and Safety of Etrolizumab Treatment in Maintenance of Disease Remission in Ulcerative Colitis (UC) Participants Who Are Naive to Tumor Necrosis Factor (TNF) Inhibitors
CompletedNCT02165215
Hoffmann-La RocheColitis, Ulcerative
Start: 2014-08-12End: 2020-04-06Updated: 2021-08-19
A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors
CompletedNCT02171429
Hoffmann-La RocheUlcerative Colitis
Start: 2014-11-14End: 2020-05-25Updated: 2021-07-23
A Study to Assess Whether Etrolizumab is a Safe and Efficacious Treatment for Participants With Moderately to Severely Active Crohn's Disease
CompletedNCT02394028
Hoffmann-La RocheCrohn Disease
Start: 2015-03-20End: 2021-09-07Updated: 2022-11-16
Open-Label Extension and Safety Study for Participants With Crohn's Disease Previously Enrolled in the Etrolizumab Phase III Study GA29144
TerminatedNCT02403323
Hoffmann-La RocheCrohn Disease
Start: 2015-06-08End: 2023-10-09Updated: 2024-12-02
A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ETROLIZUMAB AS AN INDUCTION AND MAINTENANCE TREATMENT FOR PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN*S DISEASE
Active, not recruitingNL-OMON47704
Hoffmann-La Rochechronic bowel inflamation inflammatory bowel disease
Start: 2015-12-02Target: 23Updated: 2024-02-28
AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN*S DISEASE PREVIOUSLY ENROLLED IN THE ETROLIZUMAB PHASE III PROTOCOL GA29144
RecruitingNL-OMON47567
Hoffmann-La RocheCrohn's disease inflammatory bowel disease
Start: 2016-07-08Target: 23Updated: 2024-02-28

Related Papers

2020-01-01328 citations