Ethosuximide

DRUG9 trials

Conditions

CancerChildhood Absence EpilepsyComplex Regional Pain SyndromesDepressive Disorder, Treatment-ResistantEpilepsyHeadache, MigraineIBS - Irritable Bowel SyndromeIrritable Bowel Syndrome

Early Phase 1

Investigate the Clinical Responses of Ethosuximide in Patients With Treatment-Resistant Depression.

CompletedNCT03887624

Zhejiang UniversityDepressive Disorder, Treatment-Resistant

Start: 2019-05-21End: 2021-04-01Updated: 2025-06-18

Phase 1

Comparison of a Drug and Placebo in the Prevention of Migraine Headaches

TerminatedNCT01122381

US Department of Veterans AffairsHeadache, Migraine

Start: 2011-12-31End: 2014-04-30Updated: 2015-08-19

Phase 2

Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS)

TerminatedNCT00689585

McGill University Health Centre/Research Institute of the McGill University Health CentreComplex Regional Pain Syndromes

Start: 2008-09-30End: 2010-07-31Updated: 2011-05-13

Chemotherapy Induced Painful Peripheral Neuropathy Ethosuximide (The CIN-E Study)

CompletedNCT01278004

Royal Marsden NHS Foundation TrustCancer, Peripheral Neuropathy

Start: 2010-05-31End: 2014-07-31Updated: 2016-05-26

Ethosuximide to Treat IBS

NCT02973542

University Hospital, Clermont-FerrandIrritable Bowel Syndrome

Start: 2018-04-30End: 2023-05-31Updated: 2023-01-06

Evaluation of the Efficacy and Tolerance of Low Doses of Ethosuximide in the Treatment of Peripheral Neuropathic Pain

NCT04431778

University Hospital, Clermont-FerrandPeripheral Neuropathic Pain

Start: 2020-11-01End: 2023-12-31Target: 64Updated: 2023-01-06

Phase 3

Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study

CompletedNCT00088452

Children's Hospital Medical Center, CincinnatiChildhood Absence Epilepsy, Epilepsy, Petit Mal Epilepsy +1

Start: 2004-07-31End: 2016-08-31Updated: 2020-10-14

Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome

RecruitingNCT04217733

Tanta UniversityIBS - Irritable Bowel Syndrome

Start: 2019-11-01End: 2030-12-30Target: 60Updated: 2020-01-03

Unknown Phase

Population Pharmacokinetics of Antiepileptic in Pediatrics

CompletedNCT03196466

Assistance Publique - Hôpitaux de ParisEpilepsy

Start: 2017-06-19End: 2023-06-15Updated: 2025-11-20

2026-01-02

A Potential Role of Ethosuximide and Pentoxifylline in Relieving Abdominal Pain in Irritable Bowel Syndrome Patients Treated with Mebeverine: A Randomized, Double-Blind, Placebo-Controlled Trial

Journal of Inflammation Research2022-02-012 citations

Open‐label pilot study of ethosuximide as adjunctive therapy for relieving abdominal pain related to Irritable Bowel Syndrome

Journal of Clinical Pharmacy and Therapeutics2021-11-0212 citations

Pretreatment behavior and subsequent medication effects in childhood absence epilepsy.

2017-09-1528 citations

Assessment of the effectiveness and safety of ethosuximide in the treatment of abdominal pain related to irritable bowel syndrome – IBSET: protocol of a randomised, parallel, controlled, double-blind and multicentre trial

BMJ Open2017-07-0118 citations

Second monotherapy in childhood absence epilepsy.

2016-12-1629 citations

Obesity and overweight as CAE comorbidities and differential drug response modifiers.

2016-03-3018 citations

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months.

2012-11-21165 citations

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.

2010-03-01343 citations