Equine Anti-Thymocyte Globulin

DRUG4 trials

Sponsors

National Cancer Institute (NCI), Massachusetts General Hospital, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions

Acute Liver FailureAcute Liver InjuryAmyloidosisFulminant Hepatic FailureGATA2Hepatic EncephalopathyImmune DysregulationImmunodeficiency

Phase 2

Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC

CompletedNCT00923364

National Cancer Institute (NCI)GATA2, Immunodeficiency, MDS

Start: 2009-05-07End: 2017-02-26Updated: 2020-03-12

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

RecruitingNCT01861106

National Cancer Institute (NCI)GATA2, Immunodeficiency, MDS

Start: 2013-07-24End: 2028-12-31Target: 144Updated: 2026-03-24

TReatment for ImmUne Mediated PathopHysiology

RecruitingNCT04862221

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Acute Liver Failure, Acute Liver Injury, Fulminant Hepatic Failure +2

Start: 2022-02-09End: 2027-02-01Target: 163Updated: 2026-03-10

Unknown Phase

Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease

CompletedNCT02158052

Massachusetts General HospitalAmyloidosis, Multiple Myeloma

Start: 2015-02-28End: 2021-06-22Updated: 2022-12-13

Related Papers

A novel <i>GATA2</i> distal enhancer mutation results in MonoMAC syndrome in 2 second cousins

Blood Advances2023-08-189 citations

Allogeneic Hematopoietic Stem-Cell Transplantation in Patients with GATA 2 Deficiency: Influence of Donor Stem Cell Source and Post-Transplantation Cyclophosphamide

Blood2020-11-041 citations

Sequencing of RNA in single cells reveals a distinct transcriptome signature of hematopoiesis in GATA2 deficiency

Blood Advances2020-06-1835 citations

Acquired ASXL1 mutations are common in patients with inherited GATA2 mutations and correlate with myeloid transformation

Haematologica2013-09-27135 citations

Successful allogeneic hematopoietic stem cell transplantation for GATA2 deficiency.

2011-08-03103 citations

Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications.

2011-04-2083 citations