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Epidiolex 100 mg/mL Oral Solution

DRUG5 trials

Sponsors

The University of Texas Health Science Center at San Antonio, Northwell Health, Jazz Pharmaceuticals, Elizabeth Donner, Montefiore Medical Center

Conditions

Dravet SyndromeDravet Syndrome (DS)Electrical Status Epilepticus of Slow-Wave SleepLennox Gastaut SyndromeLennox-Gastaut Syndrome (LGS)OdontalgiaOpioid Use DisorderToothache

Phase 1

CBD for Dental Pain
CompletedNCT04642404
The University of Texas Health Science Center at San AntonioOdontalgia, Toothache
Start: 2021-03-01End: 2023-03-13Updated: 2024-05-09
Efficacy of Epidiolex in Patients With Electrical Status Epilepticus of Sleep (ESES).
CompletedNCT04721691
Northwell HealthElectrical Status Epilepticus of Slow-Wave Sleep
Start: 2021-03-10End: 2024-01-17Updated: 2025-06-04

Phase 3

Dronabinol and Epidiolex to Manage Uncontrolled Residual Symptoms of Buprenorphine Initiation Trial
Not yet recruitingNCT07148206
Montefiore Medical CenterOpioid Use Disorder
Start: 2026-05-01End: 2027-12-01Target: 40Updated: 2026-02-12

Phase 4

A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex
Not yet recruitingNCT06924827
Elizabeth DonnerDravet Syndrome (DS), Lennox-Gastaut Syndrome (LGS)
Start: 2026-06-01End: 2029-06-01Target: 25Updated: 2026-03-17

Unknown Phase

Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY
RecruitingNCT05485831
Jazz PharmaceuticalsDravet Syndrome, Lennox Gastaut Syndrome, Tuberous Sclerosis Complex
Start: 2025-02-24End: 2027-02-01Target: 100Updated: 2026-02-17