Entecavir (ETV)

DRUG7 trials

Sponsors

Bristol-Myers Squibb, Gilead Sciences, Assembly Biosciences, Janssen Research & Development, LLC, Janssen Pharmaceutica N.V., Belgium

Conditions

Chronic Hepatitis BHBV (Hepatitis B Virus)HealthyHepatitis BHepatitis B, ChronicLiver Fibroses

Early Phase 1

A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment

WithdrawnNCT05550519

Janssen Pharmaceutica N.V., BelgiumHepatitis B, Chronic

Start: 2022-10-31End: 2025-08-28Updated: 2025-06-25

Phase 1

A Single and Multiple Ascending Dose Study of JNJ-64457744

TerminatedNCT05423106

Janssen Research & Development, LLCHealthy, Hepatitis B, Chronic

Start: 2022-07-04End: 2023-03-20Updated: 2025-02-03

Phase 2

Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine (FTC)/TDF, and Entecavir (ETV) in the Treatment of Chronic HBV in Subjects With Decompensated Liver Disease.

CompletedNCT00298363

Gilead SciencesChronic Hepatitis B

Start: 2006-04-30End: 2011-04-30Updated: 2013-04-25

A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infection

TerminatedNCT04398134

Assembly BiosciencesChronic Hepatitis B

Start: 2020-08-28End: 2021-12-28Updated: 2022-09-15

A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus Infection

CompletedNCT04585789

Janssen Research & Development, LLCHepatitis B

Start: 2021-03-11End: 2024-01-09Updated: 2025-05-21

Zinc Sulphate in Treatment Fibrosis in HBV Patient Receiving Antiviral Therapy

Not yet recruitingNCT07145268

Tanta UniversityHBV (Hepatitis B Virus), Liver Fibroses

Start: 2025-09-01End: 2026-09-30Target: 44Updated: 2025-08-28

Phase 3

Comparison of Entecavir to Adefovir in Chronic Hepatitis B Virus (HBV) Patients With Hepatic Decompensation

CompletedNCT00065507

Bristol-Myers SquibbHepatitis B

Start: 2003-08-31End: 2013-05-31Updated: 2013-06-24