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Enriched Hematopoetic Stem Cell Infusion

BIOLOGICAL5 trials

Sponsors

Suzanne T. Ildstad, Talaris Therapeutics Inc.

Conditions

Alpha-ThalassemiaAnemia, Sickle CellBeta-ThalassemiaBone Marrow Failure SyndromesComplex and Transfusion-dependent HemoglobinopathiesDiamond-Blackfan AnemiaHeart TransplantationMetachromatic Leukodystrophy

Phase 1

Induction of Donor Specific Tolerance in Recipients of Cardiac Allografts by Donor Stem Cell Infusion
CompletedNCT00497757
Suzanne T. IldstadHeart Transplantation
Start: 2003-07-31End: 2016-12-01Updated: 2020-08-31
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies
CompletedNCT00777231
Talaris Therapeutics Inc.Sickle Cell Disease
Start: 2005-01-31End: 2013-08-31Updated: 2020-10-14
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies
WithdrawnNCT01419704
Talaris Therapeutics Inc.Alpha-Thalassemia, Anemia, Sickle Cell, Beta-Thalassemia +4
Start: 2011-05-31End: 2016-05-31Updated: 2023-03-03

Unknown Phase

Single Patient Expanded Access Protocol: Metabolic Boost
NCT02021266
Talaris Therapeutics Inc.Metachromatic Leukodystrophy
Updated: 2020-10-08
Allogeneic Stem Cell Transplantation for the Treatment of Multiple Sclerosis (Compassionate Use)
NCT02084121
Talaris Therapeutics Inc.Metachromatic Leukodystrophy
Updated: 2022-07-18