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Enpatoran

DRUG11 trials

Sponsors

Merck Healthcare KGaA, Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany, EMD Serono Research & Development Institute, Inc., Merck

Conditions

Cutaneous Lupus ErythematosusCutaneous Lupus Erythematosus (CLE)Cutaneous Manifestations of Lupus Erythematosus With or Without Systemic DiseaseDermatomyositisHealthyImmunologyPolymyositisRenal Impairment

Phase 1

Phase 2

Phase 3

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
RecruitingNCT07332481
EMD Serono Research & Development Institute, Inc.Cutaneous Lupus Erythematosus (CLE), Systemic Lupus Erythematosus (SLE)
Start: 2026-03-10End: 2029-05-24Target: 202Updated: 2026-09-11
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
RecruitingNCT07355218
EMD Serono Research & Development Institute, Inc.Cutaneous Lupus Erythematosus, Systematic Lupus Erythematosus
Start: 2026-04-01End: 2029-05-25Target: 202Updated: 2026-09-14
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
Not yet recruitingNCT07470957
EMD Serono Research & Development Institute, Inc.Cutaneous Lupus Erythematosus (CLE), Systemic Lupus Erythematosus (SLE)
Start: 2026-03-27End: 2029-05-24Target: 202Updated: 2026-03-13
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
Not yet recruitingNCT07470970
EMD Serono Research & Development Institute, Inc.Cutaneous Lupus Erythematosus, Systematic Lupus Erythematosus
Start: 2026-03-27End: 2029-05-25Target: 202Updated: 2026-03-13
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Parallel Study to Evaluate the Efficacy and Safety of Enpatoran in Participants with Active Cutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease Receiving Standard of Care
Not yet recruitingCTIS2025-523871-44-00
Merck Healthcare KGaACutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease
Target: 16Updated: 2026-06-30
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Parallel Study to Evaluate the Efficacy and Safety of Enpatoran in Participants with Active Cutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease Receiving Standard of Care
Not yet recruitingCTIS2025-524855-30-00
Merck Healthcare KGaACutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease
Target: 15Updated: 2026-06-30
Elowen-1: A Study of Enpatoran in Cutaneous Manifestations of Lupus With or Without Systemic Disease
Active, not recruitingPACTR202608830285149
MerckImmunology
Start: 2026-05-01Target: 202Updated: 2026-09-14