ENDOXAN 50 mg
Sponsors
Centre Hospitalier Regional Universitaire, Brenus Pharma, Centre Hospitalier Universitaire Rouen, Glaxosmithkline Research & Development Limited
Conditions
Metastatic colorectal cancerUnresectable locally advanced or metastatic colorectal cancermetastatic colorectal cancer carcinomanewly diagnosed amyloid light chain amyloidosissevere forms of mucous membrane pemphigoid
Phase 1
Phase 2
REPROGRAM-02 : Induction Regorafenib in combination with metronomic cyclophosphamide, capecitabine, and low-dose aspirin followed by chemotherapy in second line metastatic colorectal cancer carcinoma
An open-label randomized phase II-III study
Not yet recruitingCTIS2024-516709-22-00
Target: 94Updated: 2025-10-08
A Phase 2, open-label, randomized, dose optimization study evaluating the efficacy and safety of belantamab mafodotin administered in combination with cyclophosphamide, bortezomib, and dexamethasone in adult participants with newly diagnosed amyloid light chain amyloidosis (ALANIS)
Not yet recruitingCTIS2025-522803-60-00
Target: 17Updated: 2026-07-22
Phase 3
CARE : Impact of Regorafenib in combination with multimodal metronomic chemotherapy (cyclophosphamide, capecitabine, and low-dose aspirin) on progression-free survival compared with standard Regorafenib for the treatment of chemo-resistant metastatic colorectal cancers
RecruitingCTIS2023-509761-21-00
Start: 2024-07-08Target: 174Updated: 2024-08-28
Randomized double blind double dummy control trial comparing the safety and efficacy of rituximab versus oral cyclophosphamide in severe forms of mucous membrane pemphigoid - (RITUX-MMP)
Active, not recruitingCTIS2024-514885-38-00
Start: 2019-07-11Target: 130Updated: 2025-10-20