Endotoxin (E. coli O:113, Reference Endotoxin)

DRUG4 trials

Sponsors

Washington University School of Medicine, Ohio State University, Radboud University Medical Center

Conditions

EndotoxemiaImmunosuppresionIntermittent Explosive DisorderLung InflammationPneumoniaSepsisSystemic Inflammation

Early Phase 1

Assessing NOS Uptake With PET Imaging in Lung Inflammation

CompletedNCT02151552

Washington University School of MedicineLung Inflammation

Start: 2014-05-31End: 2018-02-28Updated: 2018-07-23

Phase 1

PET Imaging of Endotoxin-induced iNOS Activation

CompletedNCT01407796

Washington University School of MedicinePneumonia

Start: 2010-12-31End: 2012-04-30Updated: 2014-04-21

Phase 2

Inflammatory Challenge in Human Aggression.

RecruitingNCT06665074

Ohio State UniversityIntermittent Explosive Disorder

Start: 2026-02-16End: 2030-01-01Target: 112Updated: 2026-03-27

Unknown Phase

Determining the Fingerprint of Endotoxin Tolerance

CompletedNCT06801873

Radboud University Medical CenterEndotoxemia, Immunosuppresion, Sepsis +1

Start: 2019-05-27End: 2020-08-20Updated: 2025-02-07