Empliciti 300 mg powder for concentrate for solution for infusion.
Sponsors
Regeneron Pharmaceuticals Inc., Janssen - Cilag International, University Medical Center Hamburg-Eppendorf
Conditions
Relapsed Refractory Multiple MyelomaRelapsed or Refractory Myelomamultiple myeloma
Phase 3
AN OPEN-LABEL, RANDOMIZED, PHASE 3 STUDY OF LINVOSELTAMAB (REGN5458; ANTI-BCMA X ANTI-CD3 BISPECIFIC ANTIBODY) VERSUS THE COMBINATION OF ELOTUZUMAB, POMALIDOMIDE, AND DEXAMETHASONE (EPd), IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (LINKER-MM3)
Active, not recruitingCTIS2022-501396-62-00
Start: 2023-12-12Target: 188Updated: 2025-10-26
A Phase 3 Randomized Study Comparing Talquetamab in Combination with Pomalidomide (Tal-P), Talquetamab in Combination with Teclistamab (Tal-Tec), and Investigator’s Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pomalidomide, Bortezomib, and Dexamethasone (PVd) in Participants with Relapsed or Refractory Myeloma who Have Received 1 to 4 Prior Lines of Therapy Including an Anti-CD38 Antibody and Lenalidomide
Active, not recruitingCTIS2022-502446-27-00
Start: 2024-02-26Target: 453Updated: 2026-01-13
Allogeneic stem cell transplantation vs. conventional therapy as salvage therapy for relapsed / progressive patients with multiple myeloma after a first-line therapy
CompletedCTIS2024-510590-14-00
Start: 2023-03-03End: 2025-01-30Target: 400Updated: 2025-02-05