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Empagliflozin (EMPA)

DRUG8 trials

Sponsors

Mayo Clinic, National Taiwan University Hospital, University of Sao Paulo, Ain Shams University, Kanokwan Bunsawat

Conditions

Bipolar DepressionBipolar DisorderBlood PressureBrugada Syndrome (BrS)Diabetes MellitusDiabetes Mellitus, Type 2Diabetic NephropathiesEmpgliflozin Cardioprotective Effect

Phase 2

Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes Mellitus
RecruitingNCT06729996
Mayo ClinicDiabetes Mellitus, Pancreatitis, Acute, Pancreatitis, Chronic
Start: 2025-05-29End: 2027-05-31Target: 50Updated: 2026-07-29
Empagliflozin as a Potential Therapeutic Solution for Patients With Brugada Syndrome
Not yet recruitingNCT07146880
National Taiwan University HospitalBrugada Syndrome (BrS)
Start: 2025-09-15End: 2027-09-21Target: 10Updated: 2025-09-12
SGLT2 Adjunct in T1D
CompletedNCT07591077
Ain Shams UniversityNephropathy, Diabetic, Type 1 Diabetes
Start: 2024-11-20End: 2026-02-20Updated: 2026-05-18
the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients
RecruitingNCT07692256
Ain Shams UniversityHeart Failure
Start: 2025-12-01End: 2027-02-01Target: 60Updated: 2026-07-09

Phase 3

Cardioprotective Effect of Empagliflozin in Breast Cancer Patients
Not yet recruitingNCT07815808
Tanta UniversityEmpgliflozin Cardioprotective Effect
Start: 2026-10-01End: 2028-12-31Target: 150Updated: 2026-09-24

Phase 4

Neurovascular Effects of Empagliflozin
Not yet recruitingNCT07799441
Kanokwan BunsawatBlood Pressure, Endothelial Dysfunction
Start: 2026-09-01End: 2029-01-01Target: 100Updated: 2026-09-02

Unknown Phase

Empagliflozin Adjunctive Therapy in Bipolar Depression
Not yet recruitingNCT07472920
University of Sao PauloBipolar Depression, Bipolar Disorder, Insulin Resistance
Start: 2026-03-09End: 2026-12-01Target: 20Updated: 2026-03-16
Comparing The Effect Of Empagliflozin With Dapagliflozin In Reducing Proteinuria In Diabetic Patients With Chronic Kidney Disease With eGFR More Than 45ml/Min/1.73m²
CompletedNCT07866235
Lahore General HospitalDiabetes Mellitus, Type 2, Diabetic Nephropathies, Renal Insufficiency, Chronic
Start: 2023-10-11End: 2024-04-10Updated: 2026-10-08