Emodepside

DRUG5 trials

Sponsors

Jennifer Keiser, Drugs for Neglected Diseases, Swiss Tropical & Public Health Institute

Conditions

Hookworm InfectionsOnchocerciasisStrongyloides Stercoralis InfectionStrongyloidiasisTrichurisTrichuris InfectionTrichuris Trichiura; Infection

Phase 2

Efficacy and Safety of Emodepside in Adults Infected With Trichuris Trichiura and Hookworm

CompletedNCT05017194

Jennifer KeiserHookworm Infections, Trichuris Trichiura; Infection

Start: 2021-08-02End: 2021-12-10Updated: 2022-05-27

Emodepside Phase II Trial for Treatment of Onchocerciasis

Active, not recruitingNCT05180461

Drugs for Neglected DiseasesOnchocerciasis

Start: 2021-08-30End: 2026-10-02Target: 578Updated: 2024-03-05

Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm

CompletedNCT05538767

Jennifer KeiserHookworm Infections

Start: 2022-09-16End: 2023-04-11Updated: 2023-06-15

Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis

CompletedNCT06373835

Swiss Tropical & Public Health InstituteStrongyloides Stercoralis Infection, Strongyloidiasis

Start: 2024-05-20End: 2024-09-21Updated: 2024-11-20

Efficacy and Safety of a Single Dose of Emodepside Compared to a Single Dose of Albendazole in Adolescents and Adults Infected With Trichuris Incognita

Not yet recruitingNCT07258173

Jennifer KeiserTrichuris, Trichuris Infection

Start: 2026-01-15End: 2026-05-15Target: 100Updated: 2025-12-02

Related Papers

Efficacy and safety of ascending doses of emodepside in comparison with ivermectin in adults infected with Strongyloides stercoralis in Laos: a phase 2a, dose-ranging, randomised, parallel-group, placebo-controlled, single-blind clinical trial.

2025-06-251 citations

Efficacy and safety of emodepside compared with albendazole in adolescents and adults with hookworm infection in Pemba Island, Tanzania: a double-blind, superiority, phase 2b, randomised controlled trial.

2024-08-015 citations

Emodepside for <i>Trichuris trichiura</i> and Hookworm Infection

New England Journal of Medicine2023-05-1737 citations