Eluxadoline

DRUG6 trials

Sponsors

Furiex Pharmaceuticals, Inc, Allergan, AbbVie

Conditions

Irritable Bowel SyndromeIrritable Bowel Syndrome With Diarrhea

Phase 2

Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea

CompletedNCT01130272

Furiex Pharmaceuticals, IncIrritable Bowel Syndrome

Start: 2010-04-28End: 2011-07-14Updated: 2019-10-22

Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

RecruitingNCT03339128

AbbVieIrritable Bowel Syndrome

Start: 2017-11-15End: 2026-12-31Target: 95Updated: 2025-09-19

Phase 3

Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

CompletedNCT01553591

Furiex Pharmaceuticals, IncIrritable Bowel Syndrome

Start: 2012-05-29End: 2014-07-29Updated: 2018-09-04

Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

CompletedNCT01553747

Furiex Pharmaceuticals, IncIrritable Bowel Syndrome

Start: 2012-05-29End: 2014-01-09Updated: 2018-07-30

Phase 4

Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate Control of Symptoms With Prior Loperamide Use

CompletedNCT02959983

AllerganIrritable Bowel Syndrome With Diarrhea

Start: 2016-10-25End: 2018-01-22Updated: 2019-02-15

Eluxadoline Bile Acid Malabsorption (BAM) Study

CompletedNCT03441581

AllerganIrritable Bowel Syndrome With Diarrhea

Start: 2018-02-23End: 2020-04-28Updated: 2021-05-19

Related Papers

A6 EFFECTS OF ELUXADOLINE TREATMENT ON ABDOMINAL AND BOWEL SYMPTOMS IN PATIENTS WITH IRRITABLE BOWEL SYNDROME WITH DIARRHEA REPORTING INADEQUATE SYMPTOM CONTROL WITH LOPERAMIDE: AGGREGATED RESULTS FROM PHASE 3 AND 4 CLINICAL TRIALS

Journal of the Canadian Association of Gastroenterology2020-02-011 citations

468 Effects of Eluxadoline on a Range of Bowel and Abdominal Symptoms in Patients With Irritable Bowel Syndrome With Diarrhea who Report Inadequate Symptom Control With Loperamide

The American Journal of Gastroenterology2019-10-01

Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea.

2017-02-0316 citations

Eluxadoline for Irritable Bowel Syndrome with Diarrhea

New England Journal of Medicine2016-01-20318 citations

Item-level assessment of the irritable bowel syndrome quality of life questionnaire in patients with diarrheal irritable bowel syndrome.

2014-05-0910 citations