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ELOXATINE 5 mg/ml

DRUG5 trials

Sponsors

Centre Hospitalier Universitaire De Bordeaux, Centre Hospitalier Universitaire De Dijon, Centre Hospitalier Universitaire Rouen, Fondation Franc.Cancerologie Digestive

Conditions

Rectal cancerRecurrent rectal cancer after local excisioncolon cancer and rectal with liver metastasiscolon carcinomametastatic colorectal adenocarcinomapatients admitted for an obstructive colon cancer

Phase 2

FFCD 1605- OPTIPRIME: A phase II study evaluating FOLFOX + panitumumab according to a ‘stop-and-go’ strategy with a reintroduction loop after progression on fluoropyrimidine as maintenance treatment, as the first line in patients with metastatic colorectal adenocarcinoma without a RAS mutation
CompletedCTIS2024-518740-20-00
Fondation Franc.Cancerologie Digestivemetastatic colorectal adenocarcinoma
Start: 2018-04-26End: 2025-05-19Target: 118Updated: 2024-11-14

Phase 3

A phase III randomized trial evaluating chemotherapy followed by pelvic reirradiation versus chemotherapy alone as pre-operative treatment for locally recurrent rectal cancer (GRECCAR – PRODIGE – FRENCH) - GRECCAR 15
Active, not recruitingCTIS2024-514705-62-00
Centre Hospitalier Universitaire De BordeauxRectal cancer, Recurrent rectal cancer after local excision
Start: 2019-07-08Target: 186Updated: 2024-07-04
PRODIGE 70 - CIRCULATE - CIRCULATING TUMOR DNA BASED DECISION FOR ADJUVANT TREATMENT IN COLON CANCER STAGE II
Not yet recruitingCTIS2024-515297-27-00
Centre Hospitalier Universitaire De Dijoncolon carcinoma
Target: 142Updated: 2025-03-07
Neoadjuvant Chemotherapy for Obstructive Colon cancER first Treated by cOlostomy : A randomized phase III trial - COnCERTO (French 01-18) 2019/0407/HP
RecruitingCTIS2024-516456-17-00
Centre Hospitalier Universitaire Rouenpatients admitted for an obstructive colon cancer
Start: 2024-05-07Target: 232Updated: 2025-07-17
PRODIGE 49 - OSCAR: Systemic oxaliplatin or in intra-arterial chemotherapy combined with LV5FU2 ± Irinotecan, and targeted therapy, in first-line treatment of metastatic colorectal cancer restricted to the liver
Not yet recruitingCTIS2024-518553-41-00
Fondation Franc.Cancerologie Digestivecolon cancer and rectal with liver metastasis
Target: 348Updated: 2025-12-16