Skip to content

Elinzanetant (BAY3427080)

DRUG15 trials

Sponsors

Bayer

Conditions

Healthy VolunteersHot FlashesMenopauseNight WakingVasomotor Symptoms Associated With MenopauseVasomotor Symptoms Caused by Adjuvant Endocrine Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast CancerVasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Phase 1

A Study to Learn How Much Rosuvastatin Gets Into the Blood When Taken With or Without Elinzanetant and to Learn About the Safety of Elinzanetant in Healthy Participants
CompletedNCT04889287
BayerVasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2021-05-26End: 2021-09-29Updated: 2023-08-09
A Study to Learn How Safe Elinzanetant is, How it Affects the Body, and How it Moves Into, Through and Out of the Body After Single and Multiple Doses in Japanese Healthy Female Adults
CompletedNCT04981431
BayerVasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2021-08-11End: 2022-03-13Updated: 2022-03-29
A Study to Learn What Happens to Elinzanetant in the Body When Taken With or Without Carbamazepine, and How Safe it is in Healthy Men and Women Aged 18 to 60 Years.
CompletedNCT05028608
BayerVasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2021-09-06End: 2022-01-20Updated: 2022-02-25
A Study to Learn How a Proton Pump Inhibitor Affects the Way Elinzanetant (BAY 3427080) Moves Into, Through and Out of the Body, and How Much of it Gets Absorbed by the Body When Taken as a Single and Small Radioactive Dose in Healthy Adults
CompletedNCT05061563
BayerHot Flashes, Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2021-09-30End: 2022-02-23Updated: 2022-03-17
A Study to Learn How Elinzanetant Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Kidneys That do Not Work as Well as They Should Compared to Participants Whose Kidneys Work Normally
CompletedNCT05071729
BayerVasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2021-10-14End: 2022-10-19Updated: 2025-07-14
A Study to Learn More About How Much of the Study Treatment Elinzanetant (or BAY3427080) Gets Absorbed, How Safe it is and How it Affects the Body in Healthy Female and Male Participants
CompletedNCT05351892
BayerHealthy Volunteers, Hot Flashes, Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2022-05-04End: 2022-06-20Updated: 2022-07-19
A Study to Learn More About How the Study Treatment Elinzanetant (or BAY3427080) Moves Into, Through and Out of the Body, How Safe it is and How it Affects the Body After Taking Single and Multiple Doses in Healthy Women Aged 40 to 65 Years
CompletedNCT05381142
BayerHealthy Volunteers, Hot Flashes, Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2022-05-23End: 2022-07-11Updated: 2022-07-27
A Study to Learn How the Study Drug Elinzanetant (BAY 3427080) Affects the Way the Drug Dabigatran Moves Into, Through and Out of the Body in Healthy Male and Female Participants
CompletedNCT05471817
BayerHealthy Volunteers, Hot Flashes, Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2022-08-05End: 2022-11-14Updated: 2022-11-22
A Study to Learn How Safe the Study Treatment Elinzanetant is and How it Moves Into, Through and Out of the Body When Given as Single Increasing Doses That Are Higher Than Normally Used Compared to Placebo and Moxifloxacin in Healthy Participants
CompletedNCT05481528
BayerHealthy Volunteers, Hot Flashes, Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2022-08-19End: 2023-04-28Updated: 2023-05-09
A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women
CompletedNCT06219902
BayerHot Flashes, Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Start: 2024-01-08End: 2024-04-15Updated: 2024-05-08

Phase 2

Phase 3

A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 52 Weeks in Women Who Have Been Through the Menopause
CompletedNCT05030584
BayerHot Flashes, Vasomotor Symptoms Associated With Menopause
Start: 2021-08-27End: 2024-02-12Updated: 2025-12-01
A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 26 Weeks in Women Who Have Been Through the Menopause
CompletedNCT05042362
BayerHot Flashes, Vasomotor Symptoms Associated With Menopause
Start: 2021-08-27End: 2023-11-27Updated: 2026-02-12
A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 26 Weeks in Women Who Have Been Through the Menopause (OASIS-2)
CompletedNCT05099159
BayerHot Flashes, Vasomotor Symptoms Associated With Menopause
Start: 2021-10-29End: 2023-10-10Updated: 2026-02-12
A Study to Learn More About How Well Elinzanetant Works and How Safe it is Compared to Placebo for the Treatment of Hot Flashes Caused by Anti-cancer Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer
Active, not recruitingNCT05587296
BayerHot Flashes, Vasomotor Symptoms Caused by Adjuvant Endocrine Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer
Start: 2022-10-14End: 2028-06-05Updated: 2026-07-09

Related Papers