Elimusertib
Sponsors
National Cancer Institute (NCI), M.D. Anderson Cancer Center
Conditions
Advanced Bile Duct CarcinomaAdvanced Breast CarcinomaAdvanced Cervical CarcinomaAdvanced Colorectal CarcinomaAdvanced Digestive System CarcinomaAdvanced Endometrial CarcinomaAdvanced Esophageal CarcinomaAdvanced Fallopian Tube Carcinoma
Phase 1
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer
Active, not recruitingNCT04491942
Start: 2021-08-25End: 2026-06-30Target: 74Updated: 2026-04-03
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer
Active, not recruitingNCT04514497
Start: 2021-10-20End: 2026-03-04Updated: 2025-03-06
Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines
Active, not recruitingNCT04535401
Start: 2021-08-13End: 2025-04-29Updated: 2024-10-10
Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer
Active, not recruitingNCT04576091
Start: 2022-07-06End: 2025-12-11Updated: 2024-12-13
Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors
Active, not recruitingNCT04616534
Start: 2021-06-01End: 2026-05-20Updated: 2025-05-22
BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors
WithdrawnNCT05010096
Start: 2022-03-22End: 2022-03-22Updated: 2022-05-27
Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors
Active, not recruitingNCT05071209
Start: 2021-12-22End: 2026-03-31Updated: 2026-01-23