EGFR-TKI

DRUG12 trials

Conditions

Asymptomatic Brain Metastases of Non Small Cell Lung CancerCancerCardiotoxicityDrug-Related Side Effects and Adverse Reactions (MeSH Term)EGFR Gene MutationEGFR Positive Non-small Cell Lung CancerEgfr Tyrosine Kinase InhibitorLung Adenocarcinoma

Phase 2

Study of EGFR-TKI to Asymptomatic Brain Metastases of NSCLC

NCT02250846

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyAsymptomatic Brain Metastases of Non Small Cell Lung Cancer

Start: 2015-01-31End: 2017-01-31Target: 70Updated: 2014-09-26

A Study of Hypofractionated Radiotherapy for Limited Metastatic NSCLC Harboring Sensitizing EGFR Mutations After First Line TKI Therapy

NCT02788058

First People's Hospital of HangzhouEGFR Positive Non-small Cell Lung Cancer, Lung Adenocarcinoma

Start: 2016-05-31End: 2022-05-31Target: 76Updated: 2016-06-02

EGFR-TKI With/Without Chemotherapy in NSCLC Patients With Both EGFR Mutation and BIM Deletion Polymorphism

NCT03002844

Shanghai Pulmonary Hospital, Shanghai, ChinaEGFR Gene Mutation, Nonsmall Cell Lung Cancer

Start: 2016-12-31End: 2018-12-31Target: 50Updated: 2016-12-28

Apatinib in the Treatment of Patients With EGFR T790M-Negative NSCLC

NCT03389256

Sichuan Cancer Hospital and Research InstituteLung Diseases, Neoplasms, Non-Small-Cell Lung +2

Start: 2018-12-30End: 2022-08-30Target: 144Updated: 2018-01-03

Phase 3

EGFR-TKI Concurrent With/Without WBRT in Brain Metastasis From NSCLC

NCT02714010

Sun Yat-sen UniversityNon-Small Cell Lung Cancer

Start: 2015-08-31End: 2022-12-31Target: 601Updated: 2017-10-27

EGFR-TKI With Chemotherapy in NSCLC Patients With Both EGFR Mutation and BIM Deletion Polymorphism

NCT02859077

Shanghai Pulmonary Hospital, Shanghai, ChinaNon-Small-Cell Lung Cancer

Start: 2016-08-31End: 2018-07-31Target: 100Updated: 2016-08-09

Unknown Phase

Efficacy Study of Chinese Medicine Plus EGFR-TKI Versus EGFR-TKI in Advanced Pulmonary Adenocarcinoma

NCT01745302

Shanghai University of Traditional Chinese MedicineCancer

Start: 2011-11-30End: 2016-12-31Target: 470Updated: 2016-07-13

Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced NSCLC

RecruitingNCT04324164

Hunan Province Tumor HospitalNon-small Cell Lung Cancer

Start: 2020-03-24End: 2027-12-24Target: 800Updated: 2025-01-27

Efficacy of Targeted Therapy Combined Chemotherapy in Advanced EGFR Positive NSCLC Patients

CompletedNCT04552613

The Fourth Affiliated Hospital of Zhejiang University School of MedicineEGFR Gene Mutation, Non-small-lung-cell Cancer, NSCLC

Start: 2020-11-23End: 2023-09-24Updated: 2024-01-16

Interstitial Pneumonitis Associated With EGFR-TKI and Combined With PD-1/PD-L1

CompletedNCT07036016

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyNon-Small Cell Lung Cancer (NSCLC)

Start: 2015-01-01End: 2025-05-01Updated: 2025-06-25

Cancer Therapy-Related Cardiac Dysfunction Associated With EGFR-TKIs in Advanced EGFR-mutant Non-small Cell Lung Cancer

CompletedNCT07267247

Taichung Veterans General HospitalCardiotoxicity, Drug-Related Side Effects and Adverse Reactions (MeSH Term), Egfr Tyrosine Kinase Inhibitor +1

Start: 2022-06-01End: 2024-04-30Updated: 2025-12-05

A Prospective Multicenter Study of the Association Between TCM Syndromes and EGFR-TKI Efficacy in Lung Cancer Patients

Not yet recruitingNCT07338396

Guangzhou University of Traditional Chinese MedicineNon Small Cell Lung Cancer NSCLC

Start: 2026-01-31End: 2031-07-31Target: 3000Updated: 2026-01-13

Related Papers

Chinese Herbal Medicine Combined With EGFR-TKI in EGFR Mutation-Positive Advanced Pulmonary Adenocarcinoma (CATLA): A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial