EFV/FTC/TDF

DRUG6 trials

Sponsors

Gilead Sciences, Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, Felipe Garcia

Conditions

HIVHIV InfectionsHIV-1 InfectionHepatitis C

Phase 1

Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients.

CompletedNCT01565889

Gilead SciencesHepatitis C, HIV

Start: 2012-03-31End: 2013-11-30Updated: 2014-10-01

Phase 2

High Dose Vitamin D and Calcium for Bone Health in Individuals Initiating HAART

CompletedNCT01403051

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsHIV-1 Infection

Start: 2011-09-30End: 2013-02-28Updated: 2018-10-12

Phase 3

Study to Evaluate the Safety and Efficacy of a Single Tablet Regimen of Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate Compared With a Single Tablet Regimen of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults

CompletedNCT01309243

Gilead SciencesHIV-1 Infection

Start: 2011-02-28End: 2014-02-28Updated: 2015-02-25

Study to Evaluate Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Positive Participants

CompletedNCT01815736

Gilead SciencesHIV, HIV Infections

Start: 2013-03-27End: 2020-04-01Updated: 2021-04-13

Study to Evaluate Switching From a Regimen Consisting of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) Fixed Dose Combination (FDC) to Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) FDC in Virologically-Suppressed, HIV-1 Infected Adults

CompletedNCT02345226

Gilead SciencesHIV-1 Infection

Start: 2015-01-26End: 2019-01-02Updated: 2020-01-02

Phase 4

Effects of Losartan and Antiretroviral Regimen Containing Raltegravir in Fibrosis Inflammation Mediators, Cardiovascular Risk and Neurocognitive Disorders in HIV Infected Patients Previously Effectively Treated

CompletedNCT01529749

Felipe GarciaHIV-1 Infection

Start: 2012-02-29End: 2016-02-29Updated: 2019-08-02

Related Papers

Switching from tenofovir disoproxil fumarate to tenofovir alafenamide in antiretroviral regimens for virologically suppressed adults with HIV-1 infection: a randomised, active-controlled, multicentre, open-label, phase 3, non-inferiority study

Carolina Digital Repository (University of North Carolina at Chapel Hill)2020-04-22

Vitamin D does not Modulate Immune-Mediated Bone loss during ART Initiation

Antiviral Therapy2018-07-013 citations

Superior Efficacy and Improved Renal and Bone Safety After Switching from a Tenofovir Disoproxil Fumarate- to a Tenofovir Alafenamide-Based Regimen Through 96 Weeks of Treatment

AIDS Research and Human Retroviruses2018-01-2588 citations

Racial differences in calculated bioavailable vitamin D with vitamin D/calcium supplementation

AIDS2017-08-234 citations

Switching from tenofovir disoproxil fumarate to tenofovir alafenamide coformulated with rilpivirine and emtricitabine in virally suppressed adults with HIV-1 infection: a randomised, double-blind, multicentre, phase 3b, non-inferiority study.

2017-03-0257 citations

Switching from efavirenz, emtricitabine, and tenofovir disoproxil fumarate to tenofovir alafenamide coformulated with rilpivirine and emtricitabine in virally suppressed adults with HIV-1 infection: a randomised, double-blind, multicentre, phase 3b, non-inferiority study.

2017-03-0237 citations

Switching from tenofovir disoproxil fumarate to tenofovir alafenamide in antiretroviral regimens for virologically suppressed adults with HIV-1 infection: a randomised, active-controlled, multicentre, open-label, phase 3, non-inferiority study.

2015-11-02223 citations

Vitamin D and Calcium Attenuate Bone Loss With Antiretroviral Therapy Initiation: A Randomized Trial.

2015-06-0192 citations

Sofosbuvir for chronic hepatitis C virus infection genotype 1-4 in patients coinfected with HIV.

2015-04-0119 citations