EDP1815

DRUG7 trials

Sponsors

Evelo Biosciences, Inc., Cambridge University Hospitals NHS Foundation Trust

Conditions

Atopic DermatitisCOVID-19Covid19KLH and Imiquimod Induced Skin Inflammation in Healthy VolunteersPlaque PsoriasisPsoriasis

Phase 1

A Study of EDP1815 in Healthy Participants and Participants With Mild to Moderate Psoriasis and Atopic Dermatitis

CompletedNCT03733353

Evelo Biosciences, Inc.Atopic Dermatitis, Psoriasis

Start: 2018-11-19End: 2021-10-29Updated: 2022-01-10

Evaluation of the Immunopharmacology of EDP1815 and EDP2939

CompletedNCT05682222

Evelo Biosciences, Inc.KLH and Imiquimod Induced Skin Inflammation in Healthy Volunteers

Start: 2022-06-27End: 2022-10-14Updated: 2023-05-19

Phase 2

mulTi-Arm Therapeutic Study in Pre-ICu Patients Admitted With Covid-19 - Experimental Drugs and Mechanisms

CompletedNCT04393246

Cambridge University Hospitals NHS Foundation TrustCOVID-19

Start: 2020-07-03End: 2022-06-08Updated: 2023-07-28

Safety and Efficacy of EDP1815 in the Treatment of Patients Hospitalized With COVID-19 Infection

TerminatedNCT04488575

Evelo Biosciences, Inc.Covid19

Start: 2020-08-26End: 2021-05-19Updated: 2022-12-19

A Phase 2 Study Investigating the Effect of EDP1815 in the Treatment of Mild to Moderate Plaque Psoriasis

CompletedNCT04603027

Evelo Biosciences, Inc.Plaque Psoriasis, Psoriasis

Start: 2020-09-21End: 2021-12-06Updated: 2022-12-19

A Study Investigating the Effect of EDP1815 in the Treatment of Mild, Moderate and Severe Atopic Dermatitis

CompletedNCT05121480

Evelo Biosciences, Inc.Atopic Dermatitis

Start: 2022-01-31End: 2023-03-28Updated: 2023-08-16

A Long-Term Extension Trial in Participants With Atopic Dermatitis Who Participated in Previous EDP1815 Trials

TerminatedNCT05439941

Evelo Biosciences, Inc.Atopic Dermatitis

Start: 2022-06-06End: 2023-06-07Updated: 2023-09-07

Related Papers

A randomized, double-blinded, phase 2 trial of EDP1815, an oral immunomodulatory preparation of Prevotella histicola, in adults with mild-to-moderate plaque psoriasis

Frontiers in Medicine2024-05-155 citations

Immunomodulating effects of the single bacterial strain therapy EDP1815 on innate and adaptive immune challenge responses - a randomized, placebo-controlled clinical trial.

2024-05-151 citations

Clinical translation of anti-inflammatory effects of Prevotella histicola in Th1, Th2, and Th17 inflammation

Frontiers in Medicine2023-05-0515 citations

muLTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19-Experimental drugs and mechanisms (TACTIC-E): A structured summary of a study protocol for a randomized controlled trial.

2020-07-3117 citations