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E7 TCR-T cells

BIOLOGICAL2 trials

Sponsors

Christian Hinrichs

Conditions

Anal CancerCervical CancerHPV Positive Oropharyngeal Squamous Cell CarcinomaHPV Positive Rectal Squamous Cell CarcinomaHPV-Associated Cervical CarcinomaHPV-Associated Vaginal AdenocarcinomaHPV-Related AdenocarcinomaHPV-Related Adenosquamous Carcinoma

Phase 1

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
RecruitingNCT05639972
Christian HinrichsAnal Cancer, Cervical Cancer, HPV-Associated Cervical Carcinoma +14
Start: 2025-08-11End: 2026-10-01Target: 15Updated: 2026-06-12

Phase 2

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
RecruitingNCT05686226
Christian HinrichsAnal Cancer, Cervical Cancer, HPV-Associated Vaginal Adenocarcinoma +18
Start: 2023-03-07End: 2027-01-01Target: 20Updated: 2026-06-12