Dupixent 300 mg solution for injection in pre-filled syringe
Sponsors
Regeneron Pharmaceuticals Inc., Centre Hospitalier Universitaire De Nantes, Rigshospitalet, UZ Leuven, Amsterdam UMC
Conditions
AsthmaAtopic DermatitisAtopic dermatitisAtopic eczemaBullous PemphigoidChronic rhinosinusitis with nasal polyposisChronic rhinosinusitis with nasal polypsChronic rhinosinusitis without nasal polyps
Phase 2
A Phase 2, 2-Part, Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients with Eosinophilic Gastritis with or without Eosinophilic Duodenitis
RecruitingCTIS2022-500795-62-00
Start: 2024-03-25Target: 19Updated: 2025-11-12
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients with Bullous Pemphigoid
CompletedCTIS2024-510745-34-00
Start: 2020-11-11End: 2024-12-10Target: 57Updated: 2024-09-04
An investigator-initiated, multi-center, randomized, double-blind, placebo controlled study of Dupilumab to demonstrate efficacy in subjects with nummular eczema
CompletedCTIS2024-515534-32-00
Start: 2021-03-15End: 2025-09-01Target: 70Updated: 2025-06-24
A Phase 2b, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled, Dose ranging Study to Evaluate the Efficacy and Safety of JNJ-95475939 for the Treatment of Participants with Moderate to Severe Atopic Dermatitis
Active, not recruitingCTIS2024-517814-13-00
Start: 2025-04-30Target: 86Updated: 2025-12-29
Phase 3
An Open-Label Extension Study to Assess the Long-Term Safety and Efficacy of Dupilumab in Patients ≥6 Months to <18 Years of Age With Atopic Dermatitis.
Active, not recruitingCTIS2023-509425-53-00
Start: 2015-11-09Target: 201Updated: 2025-11-04
Effect of Dupilumab an mucus plugs and inflammatory patterns in
sEvere asThmAtiC paTients — a Pilot Study (DETACT)
RecruitingCTIS2024-517567-23-00
Start: 2023-02-02Target: 10Updated: 2024-12-10
The use of dupilumab in treatment of indolent systemic mastocytosis with skin involvement
RecruitingCTIS2023-509111-89-00
Start: 2025-10-15Target: 66Updated: 2025-06-30
Phase 4
Dupilumab step-down strategy to maintain remission in adult and adolescents patients with atopic dermatitis: a non-inferiority randomized trial
Active, not recruitingCTIS2022-501179-23-00
Start: 2023-03-08Target: 256Updated: 2025-07-11
Treatment of rhinosinusitis with nasal polyposis with dupilumab and mepolizumab: A randomized, multi-centre, head-to-head comparison in real-world Danish patients
Active, not recruitingCTIS2022-502250-14-00
Start: 2023-04-13Target: 220Updated: 2025-10-29
DUPI REDUCE trial (DUPIlumab dose REDUCtion in patients with controlled atopic Eczema): a multicenter, low-intervention, non-inferiority randomized controlled trial, embedded in the TREAT NL registry.
RecruitingCTIS2023-504171-24-00
Start: 2023-08-14Target: 216Updated: 2024-12-02
A phase IV, randomized double blinded placebo-controlled study on the barrier restoring capacity of Dupilumab in type 2 airway disease: CRSwNP
RecruitingCTIS2023-504014-30-00
Start: 2023-11-14Target: 44Updated: 2023-08-28
Optimization of atopic dermatitis treatment that requires second-line systemic therapy through multiomic predictive models of treatment response (DermAtOmics-II)
RecruitingCTIS2023-506165-62-00
Start: 2023-09-25Updated: 2025-08-20
Effect of Dupilumab on nasal epithelial barrier function in patients with Chronic Rhinosinusitis with nasal polyps (CRSwNP) – an exploratory pilot study
RecruitingCTIS2023-509815-10-00
Start: 2024-05-15Target: 80Updated: 2024-05-06
AIM4: Next Step – Asthma Uncontrolled With ICS in Medium Dose (GINA 4): Next Step; Efficacy of Dupilumab Added to Medium Dose ICS/LABA in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Patients With Uncontrolled Asthma
RecruitingCTIS2023-510458-18-00
Start: 2025-03-11Target: 62Updated: 2025-10-21
WIthdrawal of DUpilumab in Severe Asthma : a randomised non-inferiority-controlled trial
RecruitingCTIS2024-516789-13-00
Start: 2025-12-15Target: 205Updated: 2025-04-28
English title: Complete remission study
Subtitle: Discontinuation of Mepolizumab or Dupilumab after at least 12 months without symptoms in patients with severe Chronic rhinosinusitis with polyps – a National Danish RCT study.
RecruitingCTIS2024-519628-25-00
Start: 2025-04-03Target: 66Updated: 2025-11-13
Long-term effect of Dupilumab on acetylsalicylic acid (ASA) intolerance and its mechanisms in patients with non-steroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD)
Not yet recruitingCTIS2024-520082-31-01
Target: 30Updated: 2025-05-20