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Dupilumab SAR231893 (REGN668)

DRUG5 trials

Sponsors

Sanofi

Conditions

AsthmaChronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)Dermatitis AtopicPrurigo Nodularis

Phase 3

Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps
CompletedNCT02898454
SanofiChronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)
Start: 2016-11-28End: 2018-11-16Updated: 2019-10-23
A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal Polyps
CompletedNCT02912468
SanofiChronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)
Start: 2016-12-05End: 2018-07-05Updated: 2019-07-25
Continuation of TRAVERSE- LTS12551 Evaluating Dupilumab Safety in Patients With Asthma (Long-Term Follow-Up)
CompletedNCT03620747
SanofiAsthma
Start: 2018-08-30End: 2022-02-18Updated: 2023-03-16

Unknown Phase

Observational Study of Patients Receiving Dupixent® for Atopic Dermatitis (AD)
Active, not recruitingNCT03992417
SanofiDermatitis Atopic
Start: 2019-06-11End: 2027-03-31Updated: 2026-08-06
A Non-interventional Study to Describe the Dupilumab Long-term Treatment, Safety and Patient Reported Outcomes in Chronic Nodular Prurigo (Prurigo Nodularis) in Clinical Routine
Active, not recruitingNCT06087627
SanofiPrurigo Nodularis
Start: 2023-12-27End: 2027-12-31Updated: 2026-07-31

Related Papers

Peak Nasal Inspiratory Flow and the Association with Nasal Obstruction in Patients with Severe CRSwNP from the SINUS-24/-52 Studies.
2025-09-27
Dupilumab improves sense of smell and clinical outcomes in patients with severe chronic rhinosinusitis with nasal polyps with anosmia.
2024-12-144 citations
One-Year Insights into the GLOBOSTAD Multinational Prospective Observational Study of Patients Receiving Dupilumab for Atopic Dermatitis.
2024-12-021 citations
Mild and symptom-free months in patients with chronic rhinosinusitis with nasal polyps treated with dupilumab
Annals of Allergy Asthma & Immunology2024-09-281 citations
Association Between Smell Loss, Disease Burden, and Dupilumab Efficacy in Chronic Rhinosinusitis with Nasal Polyps
American Journal of Rhinology and Allergy2024-09-194 citations
Dupilumab response onset, maintenance, and durability in patients with severe CRSwNP.
2024-08-142 citations
634 - Patient-reported outcomes and safety in adolescent and adult atopic dermatitis patients treated with dupilumab: real-world insights one year into the GLOBOSTAD multinational prospective observational study
British Journal of Dermatology2024-08-01
633 - Physician-assessed effectiveness and safety in adolescent and adult atopic dermatitis patients treated with dupilumab: real-world insights one year into the GLOBOSTAD multinational prospective observational study
British Journal of Dermatology2024-08-01
Dupilumab improved objective and patient-reported outcomes in patients with chronic rhinosinusitis with nasal polyps and complete nasal obstruction
2024-07-302 citations
P088 Physician-assessed effectiveness, patient-reported outcomes, and safety in adult and adolescent patients with atopic dermatitis treated with dupilumab: real-world insights 1 year into the GLOBOSTAD multinational prospective observational study
British Journal of Dermatology2024-06-28
Nasal brushing molecular endotyping distinguishes patients with chronic rhinosinusitis with nasal polyps with better response to dupilumab.
2024-06-148 citations
538 - Physician-assessed effectiveness and patient-reported outcomes in adult and adolescent patients with atopic dermatitis in the Asian subpopulation treated with dupilumab: real-world insights 1 year into the GLOBOSTAD multinational prospective observational study
British Journal of Dermatology2024-02-01
539 - Baseline patient characteristics, physician-assessed effectiveness, patient-reported outcomes, and safety in adult atopic dermatitis patients in Japan treated with dupilumab: Real-world insights one year into the GLOBOSTAD multinational prospective observational study
British Journal of Dermatology2024-02-01
531 - Physician-assessed effectiveness and patient-reported outcomes in adult and adolescent patients with atopic dermatitis treated with dupilumab: real-world insights 1 year into the GLOBOSTAD multinational prospective observational study
British Journal of Dermatology2024-02-01
Dupilumab Reduces Asthma Disease Burden and Recurrent SCS Use in Patients with CRSwNP and Coexisting Asthma.
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Dupilumab improves outcomes in patients with chronic rhinosinusitis with nasal polyps irrespective of gender: results from the <scp>SINUS</scp>‐52 trial
Clinical & Translational Immunology2024-01-012 citations
Long-Term Safety of Dupilumab in Patients With Moderate-to-Severe Asthma: TRAVERSE Continuation Study.
2023-12-309 citations
Impact of Dupilumab on Sinonasal Symptoms and Outcomes in Severe Chronic Rhinosinusitis With Nasal Polyps
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Baseline Demographics, Comorbidities, Treatment Patterns and Burden of Atopic Dermatitis in Adults and Adolescents from the GLOBOSTAD Long-Term Observational Study.
2023-10-063 citations
Prevalence of type 2 inflammatory signatures and efficacy of dupilumab in patients with chronic rhinosinusitis with nasal polyps from two phase 3 clinical trials: SINUS‐24 and SINUS‐52
International Forum of Allergy & Rhinology2023-08-0721 citations

43 more papers not shown