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Dual-target CAR-NK cells

BIOLOGICAL5 trials

Sponsors

Beijing Biotech

Conditions

Advanced/MetastaticAdvanced/Metastatic NSCLCBreast Cancer (Advanced/Metastatic)GlioblastomaHER2-positive Breast CancerHigh-Grade GliomasHigh-grade GliomaMalignant Glioma

Phase 1

Dual-Target CAR-NK Cells Directed Against MSLN, EGFR, or HER2 in Advanced NSCLC
RecruitingNCT07467863
Beijing BiotechAdvanced/Metastatic NSCLC, Non-Small Cell Lung Cancer
Start: 2026-02-02End: 2028-02-17Target: 48Updated: 2026-03-12
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
RecruitingNCT07480941
Beijing BiotechGlioblastoma, High-grade Glioma, Malignant Glioma +2
Start: 2026-02-02End: 2028-03-17Target: 36Updated: 2026-03-18
Dual-Target CAR-NK Cells for Advanced Breast Cancer HER2+ TNBC
RecruitingNCT07510802
Beijing BiotechBreast Cancer (Advanced/Metastatic), HER2-positive Breast Cancer, Triple-negative Breast Cancer
Start: 2026-02-02End: 2028-04-17Target: 60Updated: 2026-04-06
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
RecruitingNCT07551336
Beijing BiotechGlioblastoma, High-Grade Gliomas, Malignant Glioma +2
Start: 2026-03-02End: 2028-04-17Target: 36Updated: 2026-04-24
Dual-Target CAR-NK Cells Targeting MSLN, EGFR, or HER2 in Advanced NSCLC
RecruitingNCT07641023
Beijing BiotechAdvanced/Metastatic, Non-Small Cell Lung Cancer
Start: 2026-03-02End: 2028-06-17Target: 60Updated: 2026-06-11