Dual-target CAR-NK cells

BIOLOGICAL4 trials

Sponsors

Beijing Biotech

Conditions

Advanced/Metastatic NSCLCBreast Cancer (Advanced/Metastatic)GlioblastomaHER2-positive Breast CancerHigh-Grade GliomasHigh-grade GliomaMalignant GliomaNon-Small Cell Lung Cancer

Phase 1

Dual-Target CAR-NK Cells Directed Against MSLN, EGFR, or HER2 in Advanced NSCLC

RecruitingNCT07467863

Beijing BiotechAdvanced/Metastatic NSCLC, Non-Small Cell Lung Cancer

Start: 2026-02-02End: 2028-02-17Target: 48Updated: 2026-03-12

Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma

RecruitingNCT07480941

Beijing BiotechGlioblastoma, High-grade Glioma, Malignant Glioma +2

Start: 2026-02-02End: 2028-03-17Target: 36Updated: 2026-03-18

Dual-Target CAR-NK Cells for Advanced Breast Cancer HER2+ TNBC

RecruitingNCT07510802

Beijing BiotechBreast Cancer (Advanced/Metastatic), HER2-positive Breast Cancer, Triple-negative Breast Cancer

Start: 2026-02-02End: 2028-04-17Target: 60Updated: 2026-04-06

Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma

RecruitingNCT07551336

Beijing BiotechGlioblastoma, High-Grade Gliomas, Malignant Glioma +2

Start: 2026-03-02End: 2028-04-17Target: 36Updated: 2026-04-24