DU-176b

DRUG3 trials

Sponsors

Daiichi Sankyo, Daiichi Sankyo Co., Ltd.

Conditions

Arthroplasty, Replacement, HipAtrial FibrillationDeep Vein ThrombosisThrombosisTotal Knee ArthroplastyVenous Thromboembolism

Phase 2

Study of the Efficacy and Safety of DU-176b in Preventing Blood Clots in Patients Undergoing Total Hip Replacement

CompletedNCT00107900

Daiichi SankyoArthroplasty, Replacement, Hip, Thrombosis

Start: 2005-01-31End: 2005-12-31Updated: 2019-02-26

A Phase 2b Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty

CompletedNCT01203072

Daiichi Sankyo Co., Ltd.Deep Vein Thrombosis, Total Knee Arthroplasty, Venous Thromboembolism

Start: 2006-07-31End: 2008-07-31Updated: 2019-02-25

Phase 3

Study of DU-176b Aged 80 Years or Older

CompletedNCT02801669

Daiichi Sankyo Co., Ltd.Atrial Fibrillation

Start: 2016-08-05End: 2019-12-27Updated: 2020-11-19

Related Papers

Association of Edoxaban Pharmacokinetics With Bleeding in Older Patients With Atrial Fibrillation Treated With Low‐Dose Edoxaban: A Post Hoc Analysis of a Randomized Controlled Trial

Journal of the American Heart Association2026-05-14

Efficacy and Safety of Low‐Dose Edoxaban by Body Weight in Very Elderly Patients With Atrial Fibrillation: A Subanalysis of the Randomized ELDERCARE‐AF Trial

Journal of the American Heart Association2024-01-1911 citations

Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials.

2023-10-1238 citations

Laboratory Test Predictors for Major Bleeding in Elderly (≥80 Years) Patients With Nonvalvular Atrial Fibrillation Treated With Edoxaban 15 mg: Sub‐Analysis of the ELDERCARE‐AF Trial

Journal of the American Heart Association2022-09-035 citations

Effect of 15-mg Edoxaban on Clinical Outcomes in 3 Age Strata in Older Patients With Atrial Fibrillation

JAMA Cardiology2022-04-1314 citations

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

New England Journal of Medicine2020-08-30316 citations