DTX

DRUG2 trials

Sponsors

National Cancer Center, Japan, Cantargia AB

Conditions

Advanced Solid TumorsBiliary Tract CancerColorectal CancerLocally Advanced Esophageal Squamous Cell CarcinomaNon Small Cell Lung Cancer

Phase 1

A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal Carcinoma

CompletedNCT03914443

National Cancer Center, JapanLocally Advanced Esophageal Squamous Cell Carcinoma

Start: 2019-05-07End: 2025-03-31Updated: 2025-05-31

A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors

CompletedNCT05116891

Cantargia ABAdvanced Solid Tumors, Biliary Tract Cancer, Colorectal Cancer +1

Start: 2021-09-22End: 2023-06-23Updated: 2023-07-03

Related Papers

199. THE CORRELATION BETWEEN HISTOPATHOLOGICAL RESPONSE OF NIVOLUMAB-CONTAINING NEOADJUVANT CHEMOTHERAPY AND IMMUNE CELL TYPES FOR LOCALLY ADVANCED ESOPHAGEAL SQUAMOUS CELL CARCINOMA

Diseases of the Esophagus2025-08-01

271. EFFICACY OF NEOADJUVANT CF OR DCF, FLOT PLUS NIVOLUMAB FOR RESECTABLE LOCALLY ADVANCED ESOPHAGEAL SQUAMOUS CELL CARCINOMA (JCOG1804E: FRONTIER)

Diseases of the Esophagus2024-09-01

FRONTiER: A feasibility trial of nivolumab with neoadjuvant CF or DCF, FLOT therapy for locally advanced esophageal carcinoma (JCOG1804E)—Primary safety and short-term efficacy results for cohort E.

Journal of Clinical Oncology2024-01-202 citations

Safety, efficacy and biomarker data in patients with non-small cell lung cancer treated with the anti-IL1RAP antibody nadunolimab in combination with platinum doublet.

Journal of Clinical Oncology2023-06-01

FRONTiER: A feasibility trial of nivolumab with neoadjuvant CF or DCF, FLOT therapy for locally advanced esophageal carcinoma (JCOG1804E)—Short-term results for cohorts C and D.

Journal of Clinical Oncology2022-01-1922 citations

FRONTiER: A feasibility trial of nivolumab with neoadjuvant CF or DCF therapy for locally advanced esophageal carcinoma (JCOG1804E)—The short-term results of cohort A and B.

Journal of Clinical Oncology2021-01-2019 citations

A phase II, single-centre trial of neoadjuvant toripalimab plus chemotherapy in locally advanced esophageal squamous cell carcinoma

Journal of Thoracic Disease2020-11-0142 citations

Feasibility Study of Nivolumab as Neoadjuvant Chemotherapy for Locally Esophageal Carcinoma: FRONTiER (JCOG1804E)

Future Oncology2020-05-1267 citations