DSM265 400mg

DRUG2 trials

Sponsors

Medicines for Malaria Venture

Conditions

Plasmodium Falciparum MalariaPlasmodium Falciparum, MalariaPlasmodium Vivax Malaria

Phase 1

DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria

CompletedNCT02450578

Medicines for Malaria VenturePlasmodium Falciparum, Malaria

Start: 2015-10-31End: 2016-04-30Updated: 2021-01-13

Phase 2

DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax

CompletedNCT02123290

Medicines for Malaria VenturePlasmodium Falciparum Malaria, Plasmodium Vivax Malaria

Start: 2016-01-31End: 2016-01-31Updated: 2016-06-22

Related Papers

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study.

2018-06-13103 citations

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection.

2017-03-2875 citations