DSM265

DRUG3 trials

Sponsors

Medicines for Malaria Venture

Conditions

HealthyMalaria

Phase 1

A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265

CompletedNCT02389348

Medicines for Malaria VentureMalaria

Start: 2015-02-28End: 2015-06-30Updated: 2015-10-07

DSM265 Prophylaxis of Plasmodium Falciparum Malaria

CompletedNCT02562872

Medicines for Malaria VentureHealthy

Start: 2016-03-31End: 2017-05-31Updated: 2022-01-14

A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection

TerminatedNCT02573857

Medicines for Malaria VentureMalaria

Start: 2015-10-31End: 2016-05-31Updated: 2020-06-05

Related Papers

Antimalarial Activity of Artefenomel Against Asexual Parasites and Transmissible Gametocytes During Experimental Blood-Stage <i>Plasmodium vivax</i> Infection

The Journal of Infectious Diseases2020-05-2615 citations

A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers.

2019-12-2043 citations

DSM265 at 400 Milligrams Clears Asexual Stage Parasites but Not Mature Gametocytes from the Blood of Healthy Subjects Experimentally Infected with <i>Plasmodium falciparum</i>.

2019-03-2734 citations

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection.

2017-03-2875 citations