DRSP/EE

DRUG4 trials

Sponsors

Vertex Pharmaceuticals Incorporated, Institut de Recherches Internationales Servier (I.R.I.S.)

Conditions

Autosomal Dominant Polycystic Kidney Disease (ADPKD)Healthy Adult Female ParticipantsPain

Phase 1

Evaluation of the Effect of Suzetrigine (SUZ) on the Pharmacokinetics of Oral Contraceptives in Healthy Female Participants

CompletedNCT06820307

Vertex Pharmaceuticals IncorporatedPain

Start: 2025-02-25End: 2025-04-29Updated: 2025-05-29

Effects of VX-407 on the Pharmacokinetics of Oral Contraceptives in Healthy Participants

CompletedNCT07074327

Vertex Pharmaceuticals IncorporatedAutosomal Dominant Polycystic Kidney Disease (ADPKD)

Start: 2025-07-11End: 2026-02-27Updated: 2026-03-30

A Drug-drug Interaction Study of Vorasidenib and a Combined Oral Contraceptive in Healthy Female Participants

CompletedNCT07235774

Institut de Recherches Internationales Servier (I.R.I.S.)Healthy Adult Female Participants

Start: 2025-11-05End: 2026-03-13Updated: 2026-05-12

Effects of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives

Not yet recruitingNCT07792408

Vertex Pharmaceuticals IncorporatedAutosomal Dominant Polycystic Kidney Disease (ADPKD)

Start: 2026-08-28End: 2027-03-20Target: 148Updated: 2026-08-28