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Drospirenone

DRUG11 trials

Sponsors

Chemo Research S.L., University Of Debrecen, Center for Epidemiology and Health Research, Germany, Insud Pharma, Janssen Pharmaceutica N.V., Belgium

Conditions

Advanced MalignanciesCardiovascular System Diseases (&Amp; [Cardiac])Change in Bone Mineral DensityContraceptionHealthy FemaleHypertensionOral contraceptionOverweight

Phase 1

A Study of Milvexian in Healthy Adult Females
CompletedNCT05706753
Janssen Pharmaceutica N.V., BelgiumHealthy Female
Start: 2023-01-25End: 2023-07-20Updated: 2025-03-30
A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese
CompletedNCT06039826
Eli Lilly and CompanyOverweight
Start: 2023-09-12End: 2024-07-11Updated: 2024-07-26
Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study
RecruitingNCT06345560
Chulalongkorn UniversityContraception
Start: 2024-04-18End: 2026-07-01Target: 16Updated: 2026-03-19
A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies
RecruitingNCT07340190
Novartis PharmaceuticalsAdvanced Malignancies
Start: 2026-06-12End: 2028-04-07Target: 24Updated: 2026-10-09

Phase 3

Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females
CompletedNCT05461573
Insud PharmaChange in Bone Mineral Density, Contraception
Start: 2022-08-02End: 2025-05-27Updated: 2025-10-08

Phase 4

A multicenter, open-label, controlled study to investigate the effect of either LF111 or Drospirenone chewable tablets on bone mineral density (BMD) in adolescent and adult women in comparison with non-users of hormonal contraceptive methods
Active, not recruitingCTIS2024-512347-23-00
Chemo Research S.L.Oral contraception
Start: 2022-08-22Target: 940Updated: 2025-09-04
A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia
Not yet recruitingNCT07293728
Oregon Health and Science UniversityHypertension, Preeclampsia
Start: 2026-07-31End: 2026-12-31Target: 50Updated: 2025-12-19
Evaluation of Thrombin Generation and Thrombosis Risk in Women on Hormonal Contraceptives with a Focus on Modifiable Risk Factors
Not yet recruitingCTIS2026-527084-15-00
University Of DebrecenVenous Thromboembolism Risk associated with Hormonal Contraceptives
Target: 350Updated: 2026-10-07

Unknown Phase

European Active Surveillance Study (EURAS)
CompletedNCT00302848
Center for Epidemiology and Health Research, GermanyContraception
Start: 2000-11-30End: 2005-12-31Updated: 2009-11-20
Drospirenone Only Pills and Cervical Mucus Changes: A Pre- and Post-Bariatric Surgery Study
RecruitingNCT06345586
Chulalongkorn UniversityContraception
Start: 2024-04-18End: 2026-07-01Target: 16Updated: 2026-03-18
Prospective Evaluation on the Role Exerted by Hormonal Contraceptives on 24-h Blood Pressure. A Prospective Observational Study
RecruitingNCT07061093
Ospedale Policlinico San MartinoCardiovascular System Diseases (&Amp; [Cardiac])
Start: 2023-10-10End: 2026-01-31Target: 96Updated: 2025-07-11