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Doxycycline Hyclate

DRUG11 trials

Sponsors

Warner Chilcott, Metropolitan Autonomous University, Sun Yat-sen University, Unity Health Toronto, University of Alberta

Conditions

AcneAcne VulgarisAutoimmune DiseasesBacterial Sexually Transmitted DiseasesEndocrine System DiseasesExudative Macular DegenerationEye Diseases, HereditaryGraves Disease

Phase 2

Double-blind-randomized,Placebo Controlled Trial for Chemotherapy-associated Oral Mucositis Using Doxycycline Hyclate
NCT01087476
Metropolitan Autonomous UniversityMucositis
Start: 2010-05-31End: 2013-02-28Target: 164Updated: 2010-03-16
Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy
NCT02203682
Sun Yat-sen UniversityAutoimmune Diseases, Endocrine System Diseases, Eye Diseases, Hereditary +6
Start: 2014-07-31End: 2022-07-31Target: 100Updated: 2021-11-17
Doxycycline for Hereditary Hemorrhagic Telangiectasia
CompletedNCT03397004
Unity Health TorontoHereditary Hemorrhagic Telangiectasia (HHT)
Start: 2018-09-12End: 2021-03-01Updated: 2025-04-01
Doxycycline to Protect Heart Muscle After Heart Attacks
CompletedNCT03508232
University of AlbertaHeart Failure, ST Segment Elevation Myocardial Infarction
Start: 2020-01-06End: 2025-08-26Updated: 2026-04-13
MMP-9 Inhibition for Recalcitrant Wet AMD
RecruitingNCT04504123
University of IowaExudative Macular Degeneration, Wet Age-related Macular Degeneration
Start: 2020-11-04End: 2027-03-01Target: 50Updated: 2026-04-02

Phase 4

Treatment of Acne Vulgaris With Doryx Tablets Compared to Doxycyline Hyclate
CompletedNCT00635609
Warner ChilcottAcne Vulgaris
Start: 2008-03-31End: 2008-09-30Updated: 2012-04-20
A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)
CompletedNCT04451330
Galderma R&DAcne Vulgaris
Start: 2020-07-29End: 2021-04-26Updated: 2022-05-10
Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
Active, not recruitingNCT04582383
University of PennsylvaniaAcne
Start: 2022-03-30End: 2027-07-31Target: 350Updated: 2026-08-25
Subantimicrobial Doxycycline in Acne
CompletedNCT05399290
Michigan State UniversityAcne Vulgaris, Pediatrics
Start: 2020-11-19End: 2021-11-08Updated: 2023-04-03

Unknown Phase

Doxycycline Intervention for Bacterial STI ChemoprOphylaxis (DISCO)
RecruitingNCT04762134
Jonathan Troy GrennanBacterial Sexually Transmitted Diseases
Start: 2023-06-02End: 2027-06-30Target: 560Updated: 2024-08-05
Multi-model Image of Doxycycline in TAO
RecruitingNCT05112211
Sun Yat-sen UniversityThyroid Associated Ophthalmopathy
Start: 2022-01-01End: 2026-12-01Target: 20Updated: 2023-11-22

Related Papers

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Challenges in designing a randomized, double-blind noninferiority trial for treatment of acne: The SD-ACNE trial
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Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasia
Orphanet Journal of Rare Diseases2022-11-0716 citations
Doxycycline vs Placebo at 12 Weeks in Patients With Mild Thyroid-Associated Ophthalmopathy
JAMA Ophthalmology2022-09-298 citations
Double-blind placebo-controlled randomized clinical trial evaluating doxycycline effects on chemotherapy-induced oral mucositis.
2017-09-251 citations