double-unit umbilical cord blood transplantation

PROCEDURE5 trials

Sponsors

National Cancer Institute (NCI), Fred Hutchinson Cancer Center, Case Comprehensive Cancer Center, University of Medicine and Dentistry of New Jersey

Conditions

Accelerated Phase Chronic Myelogenous LeukemiaAcute Biphenotypic LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)

Phase 1

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

CompletedNCT00343798

Fred Hutchinson Cancer CenterAccelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission +86

Start: 2006-04-30Updated: 2015-02-11

Phase 2

Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia

CompletedNCT00025038

National Cancer Institute (NCI)Juvenile Myelomonocytic Leukemia

Start: 2001-06-30Updated: 2013-04-11

Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease

CompletedNCT00719888

Fred Hutchinson Cancer CenterAcute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia +16

Start: 2005-11-18End: 2024-12-19Updated: 2025-03-07

Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

CompletedNCT01093586

Case Comprehensive Cancer CenterAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7) +73

Start: 2007-09-30End: 2015-12-31Updated: 2019-01-23

Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies

WithdrawnNCT01652014

University of Medicine and Dentistry of New JerseyAccelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission +51

Start: 2014-01-31End: 2017-01-31Updated: 2016-07-14