Dose-intensified TMZ

DRUG2 trials

Sponsors

University of Florida

Conditions

Brain Stem GliomaDiffuse Intrinsic Pontine Glioma (DIPG)High Grade GliomaMalignant Glioma

Phase 1

Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas

TerminatedNCT03334305

University of FloridaHigh Grade Glioma, Malignant Glioma

Start: 2018-08-27End: 2025-03-20Updated: 2026-04-23

Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)

TerminatedNCT03396575

University of FloridaBrain Stem Glioma, Diffuse Intrinsic Pontine Glioma (DIPG)

Start: 2018-07-17End: 2025-03-20Updated: 2025-10-29

Related Papers

IMMU-27. IMMUNE CHECKPOINT BLOCKADE OF EX VIVO EXPANDED T CELLS FOR USE IN ADOPTIVE CELLULAR THERAPY (ACT) FOR GLIOBLASTOMA

Neuro-Oncology2019-11-01

Abstract 1194: Adoptive cellular therapy overcomes tumor-induced dysregulation of myelopoiesis

Cancer Research2019-07-01

Abstract 1194: Adoptive cellular therapy overcomes tumor-induced dysregulation of myelopoiesis

Tumor Biology2019-07-01

TMIC-29. REPROGRAMMING BONE MARROW OF TUMOR-BEARING HOSTS FOR GLIOMA IMMUNOTHERAPY

Neuro-Oncology2018-11-01