Donor Leukocyte Infusion (DLI)

BIOLOGICAL3 trials

Sponsors

King's College Hospital NHS Trust, Washington University School of Medicine, Sawa Ito, MD

Conditions

Acute Myeloid LeukemiaLeukemia, Myeloid, AcuteMyelodysplastic Syndromes

Phase 1

Lentivirus Transduced Acute Myeloid Leukaemia Blasts Expressing B7.1 (CD80) and IL-2

King's College Hospital NHS TrustLeukemia, Myeloid, Acute

Start: 2008-05-31End: 2012-02-29Target: 24Updated: 2008-07-18

Azacitidine After Chemotherapy and Donor Lymphocyte Infusion in Patients With Relapsed Acute Myeloid Leukemia or Myelodysplastic Syndrome Previously Treated With Donor Stem Cell Transplant

CompletedNCT01390311

Washington University School of MedicineLeukemia, Myeloid, Acute, Myelodysplastic Syndromes

Start: 2012-04-30End: 2015-04-30Updated: 2015-04-27

Phase 2

Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation

RecruitingNCT06529731

Sawa Ito, MDAcute Myeloid Leukemia, Myelodysplastic Syndromes

Start: 2024-09-23End: 2029-10-31Target: 57Updated: 2026-08-11