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Docosahexaenoic acid (DHA)

DIETARY_SUPPLEMENT16 trials

Sponsors

National Institute on Alcohol Abuse and Alcoholism (NIAAA), Beth Israel Deaconess Medical Center, University of Massachusetts, Worcester, Mayo Clinic, University of Milan

Conditions

Acute Lymphoblastic LeukemiaArrhythmiaAutismBreast CancerColitisConcussionCystic FibrosisFetal Growth Retardation

Phase 1

Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress
CompletedNCT00014027
National Institute on Alcohol Abuse and Alcoholism (NIAAA)Healthy
Start: 2001-04-04End: 2008-04-11Updated: 2017-07-02
Evaluation of DHA for the Treatment of PSC
CompletedNCT00325013
Beth Israel Deaconess Medical CenterColitis, Primary Sclerosing Cholangitis
Start: 2005-12-31End: 2012-05-31Updated: 2015-03-11
Reducing Dyskinesia in Parkinson's Disease With Omega-3 Fatty Acids
CompletedNCT01563913
VA Office of Research and DevelopmentParkinson's Disease
Start: 2012-10-31End: 2016-06-30Updated: 2018-06-29
Enteral Administration of Docosahexaenoic Acid to Prevent Necrotizing Enterocolitis in Preterm Neonates
CompletedNCT01745510
Coordinación de Investigación en Salud, MexicoNecrotizing Enterocolitis
Start: 2012-10-31End: 2017-10-31Updated: 2021-03-24
DHA For The Treatment of Pediatric Concussion Related to Sports Injury
CompletedNCT01903525
University of Texas Southwestern Medical CenterConcussion, Mild Traumatic Brain Injury
Start: 2013-09-30End: 2017-08-31Updated: 2021-01-11
A Dose Response Investigation of Docosahexaenoic Acid (DHA)
CompletedNCT06294067
University of TorontoNutrition, Healthy
Start: 2024-02-26End: 2025-03-26Updated: 2025-10-03

Phase 2

Effects of Docosahexaenoic Acid (DHA) on Heart Rate Variability in Elderly Patients
CompletedNCT00749307
Campus Bio-Medico UniversityArrhythmia
Start: 2008-06-30End: 2009-11-30Target: 50Updated: 2009-11-25
Effect of Enteral Docosahexaenoic Acid Administration in Children With Acute Lymphoblastic Leukemia
CompletedNCT01051154
Coordinación de Investigación en Salud, MexicoAcute Lymphoblastic Leukemia, Malnutrition
Start: 2010-09-30End: 2016-08-31Updated: 2016-08-22
Docosahexaenoic Acid (DHA) for Women With Breast Cancer in the Neoadjuvant Setting
Active, not recruitingNCT03831178
AHS Cancer Control AlbertaBreast Cancer
Start: 2019-08-28End: 2030-09-30Updated: 2025-06-26

Phase 3

A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders
NCT02336243
Pontificia Universidad Catolica de ChileFetal Growth Retardation, Preeclampsia, Premature Birth +1
Start: 2015-05-31End: 2018-04-30Target: 2400Updated: 2015-11-04

Unknown Phase

Use of Formula Fortified With DHA in Infants With Cystic Fibrosis
CompletedNCT00530244
University of Massachusetts, WorcesterCystic Fibrosis
Start: 2003-03-31End: 2011-10-31Updated: 2018-03-07
Docosahexaenoic Acid in the Treatment of Autism
CompletedNCT00577447
Mayo ClinicAutism
Start: 2005-10-31End: 2007-11-30Updated: 2015-04-28
Docosaexahenoic Acid and Gross Motor Milestones in Infants
CompletedNCT00610922
University of MilanHealthy
Start: 2005-05-31End: 2006-12-31Updated: 2008-02-08
Docosahexaenoic Acid (DHA) Administration and Length of Gestation: a Feasibility Study
WithdrawnNCT00691418
Kaiser PermanentePremature Birth
Start: 2008-07-31End: 2009-08-31Updated: 2015-03-06
The Effect of Docosahexaenoic Acid Supplementation on Biomarkers of Concussion Over the Course of a Year in Canadian National Rugby Players
CompletedNCT03582267
Texas Christian UniversityHead Trauma
Start: 2017-08-01End: 2019-08-01Updated: 2019-09-13
Evaluation of the Effect of Citicoline and Docosahexaenoic Acid (DHA) on the Visual Function of Patients With Glaucoma
CompletedNCT05527106
Institut Catala de RetinaGlaucoma
Start: 2015-03-12End: 2022-05-25Updated: 2022-09-02

Related Papers

Exploratory outcomes of the DHA WIN randomized controlled trial: Supplementing women with docosahexaenoic acid did not reduce the impact of neoadjuvant breast cancer chemotherapy on quality of life or exercise behaviour
PLoS ONE2025-05-02
Baseline Quality of Life Questionnaire.
OPAL (Open@LaTrobe) (La Trobe University)2025-05-02
DHA-WIN Study Protocol.
OPAL (Open@LaTrobe) (La Trobe University)2025-05-02
Post-intervention Quality of Life Questionnaire.
OPAL (Open@LaTrobe) (La Trobe University)2025-05-02
Consort Checklist.
OPAL (Open@LaTrobe) (La Trobe University)2025-05-02
Pilot study on the effect of supplementation with long-chain ω-3 polyunsaturated fatty acids on body composition in children with acute lymphoblastic leukemia: randomized clinical trial.
2023-07-1311 citations
Effect of long-chain omega-3 polyunsaturated fatty acids on cardiometabolic factors in children with acute lymphoblastic leukemia undergoing treatment: a secondary analysis of a randomized controlled trial
Frontiers in Endocrinology2023-04-1411 citations
A Pilot Randomized Controlled Trial of Docosahexaenoic Acid for the Treatment of Sport-Related Concussion in Adolescents
Clinical Pediatrics2022-06-1921 citations
Comparing docosahexaenoic acid (DHA) concomitant with neoadjuvant chemotherapy versus neoadjuvant chemotherapy alone in the treatment of breast cancer (DHA WIN): protocol of a double-blind, phase II, randomised controlled trial
BMJ Open2019-09-0124 citations
Docosahexaenoic acid supplementation and time at achievement of gross motor milestones in healthy infants: a randomized, prospective, double-blind, placebo-controlled trial.
2008-12-0325 citations