Docetaxel, Cisplatin

DRUG4 trials

Sponsors

National Taiwan University Hospital, Spanish Lung Cancer Group, National Cancer Center, Korea, Samsung Medical Center

Conditions

BRCA1 MutationGastric CancerNasopharyngeal CancerNon Small Cell Lung CancerNon-small Cell Lung Cancer

Phase 2

Docetaxel Plus Cisplatin Followed by Gemcitabine Versus Gemcitabine Plus Cisplatin Followed by Docetaxel for Non-Small Cell Lung Cancer (NSCLC)

CompletedNCT00173888

National Taiwan University HospitalNon-small Cell Lung Cancer

Start: 2003-07-31End: 2012-11-30Updated: 2012-12-06

Docetaxel Versus Docetaxel Plus Cisplatin Versus Docetaxel Plus S-1 as Second-line Chemotherapy in Metastatic Gastric Cancer

National Cancer Center, KoreaGastric Cancer

Start: 2008-11-30End: 2011-05-31Target: 144Updated: 2009-09-21

Weekly Docetaxel Plus Cisplatin as the First-line Therapy for Nasopharyngeal Cancer

Samsung Medical CenterNasopharyngeal Cancer

Start: 2006-07-31Target: 51Updated: 2011-03-10

Phase 3

Study to Evaluate Treatment Customized According to RAP80 and BRCA1 in Patients With Advanced Lung Carcinoma

TerminatedNCT00617656

Spanish Lung Cancer GroupBRCA1 Mutation, Non Small Cell Lung Cancer

Start: 2008-02-29End: 2015-04-30Updated: 2024-01-30

Related Papers

Association of PALB2 Messenger RNA Expression with Platinum-Docetaxel Efficacy in Advanced Non-Small Cell Lung Cancer.

2018-11-2213 citations

Two biomarker-directed randomized trials in European and Chinese patients with nonsmall-cell lung cancer: the BRCA1-RAP80 Expression Customization (BREC) studies.

2014-08-2719 citations

Treatment Based on BRCA1 and RAP80 Does Not Extend PFS

MD Conference Express2013-07-01

Interim analysis of the Spanish Lung Cancer Group (SLCG) BRCA1-RAP80 Expression Customization (BREC) randomized phase III trial of customized therapy in advanced non-small cell lung cancer (NSCLC) patients (p) (NCT00617656/GECP-BREC).

Journal of Clinical Oncology2013-06-205 citations

Customized chemotherapy in metastatic non-small cell lung cancer (NSCLC).

2013-06-011 citations