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DOAC

DRUG5 trials

Sponsors

Kansas City Heart Rhythm Institute, Population Health Research Institute, Insel Gruppe AG, University Hospital Bern, Academisch Medisch Centrum

Conditions

Atrial FibrillationAtrial Fibrillation (AF)Bleeding Post Cardiac SurgeryIndication for AnticoagulationIschemic StrokeOral AnticoagulationP2Y12 InhibitorPercutaneous Coronary Intervention (PCI)

Phase 3

The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial
RecruitingNCT04284839
Population Health Research InstituteBleeding Post Cardiac Surgery, Indication for Anticoagulation
Start: 2021-07-18End: 2027-06-30Target: 3500Updated: 2025-09-29

Phase 4

DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation
CompletedNCT02666742
Kansas City Heart Rhythm InstitutePremature Ventricular Contraction, Stroke, Ventricular Tachycardia
Start: 2017-02-16End: 2021-04-30Updated: 2022-08-22
Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
RecruitingNCT05955365
Insel Gruppe AG, University Hospital BernAtrial Fibrillation (AF), Oral Anticoagulation, P2Y12 Inhibitor +1
Start: 2023-12-18End: 2026-12-31Target: 3010Updated: 2024-10-17

Unknown Phase

Long-term outcome after heparin plus edoxaban versus heparin plus vitamin K antagonists for acute deep vein thrombosis and pulmonary embolism
Active, not recruitingNL-OMON42861
Academisch Medisch Centrumkwaliteit van leven embolism thrombosis
Start: 2017-04-25Target: 255Updated: 2024-02-28
Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy
RecruitingNCT05976685
Insel Gruppe AG, University Hospital BernAtrial Fibrillation, Ischemic Stroke
Start: 2024-05-01End: 2028-06-01Target: 482Updated: 2026-02-23