DNTH103

DRUG6 trials

Sponsors

Dianthus Therapeutics Inc., Dianthus Therapeutics

Conditions

Chronic Inflammatory Demyelinating PolyneuropathyGeneralized Myasthenia GravisMultifocal Motor NeuropathyMyasthenia Gravis, Generalized

Phase 2

A Phase 2 Study to Evaluate DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC)

Active, not recruitingNCT06282159

Dianthus TherapeuticsMyasthenia Gravis, Generalized

Start: 2024-02-23End: 2027-08-31Updated: 2025-10-07

A PHASE 2, RANDOMIZED, BLINDED, PLACEBOCONTROLLED, STUDY TO EVALUATE SAFETY, TOLERABILITY, PHARMACOMETRICS, AND EFFICACY OF DNTH103 IN ADULTS WITH GENERALIZED MYASTHENIA GRAVIS (MAGIC)

RecruitingCTIS2024-512865-15-00

Dianthus Therapeutics Inc.Generalized Myasthenia Gravis

Start: 2024-09-03Target: 54Updated: 2025-10-27

A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy

RecruitingNCT06537999

Dianthus TherapeuticsMultifocal Motor Neuropathy

Start: 2024-09-17End: 2028-03-31Target: 36Updated: 2025-10-06

A Phase 2, Randomized, Double-Blinded, Placebo-Controlled, Study to Evaluate Safety, Tolerability, Pharmacometrics, and Efficacy of DNTH103 in Adults with Multifocal Motor Neuropathy (MOMENTUM)

RecruitingCTIS2024-513128-40-00

Dianthus Therapeutics Inc.Multifocal Motor Neuropathy

Start: 2025-02-06Target: 11Updated: 2026-01-12

Phase 3

A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

RecruitingNCT06858579

Dianthus TherapeuticsChronic Inflammatory Demyelinating Polyneuropathy

Start: 2025-02-10End: 2030-12-31Target: 480Updated: 2026-03-27

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of DNTH103 in Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

RecruitingCTIS2024-517529-26-00

Dianthus Therapeutics Inc.Chronic Inflammatory Demyelinating Polyneuropathy

Start: 2025-08-04Target: 156Updated: 2026-01-26