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DMARDs

DRUG16 trials

Sponsors

Wyeth is now a wholly owned subsidiary of Pfizer, Hoffmann-La Roche, JW Pharmaceutical, Columbia University, Mycenax Biotech Inc.

Conditions

Arthritis, PsoriaticArthritis, RheumatoidCombination With DMARDsConnective Tissue DiseasesInterstitial Lung DiseasePirfenidoneRheumatoid ArthritisSpondylitis, Ankylosing

Phase 1

Phase 3

A Study of Tocilizumab in Combination With Disease-Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Moderate to Severe Active Rheumatoid Arthritis With an Inadequate Response to DMARDs
CompletedNCT00996606
Hoffmann-La RocheRheumatoid Arthritis
Start: 2009-10-31End: 2012-04-30Updated: 2017-06-19
Efficacy and Safety of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis
CompletedNCT01211834
JW PharmaceuticalRheumatoid Arthritis
Start: 2009-10-31End: 2010-10-31Target: 90Updated: 2010-11-03
To Evaluate 1 Year Extension Study of the Efficacy and Safety of Tocilizumab in Patients With Moderate to Severe Rheumatoid Arthritis
CompletedNCT01256736
JW PharmaceuticalRheumatoid Arthritis
Start: 2010-03-31End: 2013-11-30Updated: 2013-11-20
A Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination With DMARDs Versus DMARDs Alone in Patients With Rheumatoid Arthritis
NCT01787149
Mycenax Biotech Inc.Combination With DMARDs
Start: 2013-09-30End: 2019-12-31Target: 98Updated: 2018-04-17
A Study to Evaluate Efficacy of Tocilizumab Administered as Monotherapy or in Combination With Methotrexate and/or Other Disease Modifying Antirheumatic Drugs (DMARDs) in Rheumatoid Arthritis (RA) Participants
CompletedNCT01941940
Hoffmann-La RocheRheumatoid Arthritis
Start: 2013-09-05End: 2016-07-05Updated: 2017-07-11
A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent
CompletedNCT02046603
Hoffmann-La RocheRheumatoid Arthritis
Start: 2014-03-04End: 2016-08-04Updated: 2018-12-07

Phase 4

Unknown Phase

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