Disulfiram (DSF)

DRUG3 trials

Sponsors

John P. Fruehauf, University of Oklahoma, Case Comprehensive Cancer Center

Conditions

Brain (Nervous System) CancersInflammationObesityRheumatoid ArthritisStage IV Melanoma

Phase 1

Disulfiram in Patients With Metastatic Melanoma

CompletedNCT00256230

John P. FruehaufStage IV Melanoma

Start: 2002-01-31End: 2007-08-31Updated: 2016-12-08

Study of Disulfiram to Reduce Myeloid Immunosuppression and Steroid Dependence in Resectable High Grade Glioma

Not yet recruitingNCT07719127

Case Comprehensive Cancer CenterBrain (Nervous System) Cancers

Start: 2026-10-01End: 2027-12-31Target: 20Updated: 2026-07-22

Phase 2

Disulfiram in Rheumatoid Arthritis

Not yet recruitingNCT07534332

University of OklahomaInflammation, Obesity, Rheumatoid Arthritis

Start: 2026-09-01End: 2028-04-30Target: 20Updated: 2026-07-27