Diroximel Fumarate
Sponsors
Novartis Pharma AG, Centre Hospitalier Universitaire De Montpellier, Monash University, Biogen
Conditions
Adherence, MedicationHealthy VolunteersMultiple SclerosisMultiple sclerosisRelapsing Forms of MSRelapsing Forms of Multiple Sclerosisrelapsing multiple sclerosis (RMS)
Phase 1
Phase 3
A Study of Diroximel Fumarate (DRF) in Adult Participants From the Asia-Pacific Region With Relapsing Forms of Multiple Sclerosis (RMS)
CompletedNCT05083923
Start: 2021-11-18End: 2024-09-11Updated: 2025-10-24
An Open-Label, Rater-Blind, Randomized, Multi-Center, Parallel-Arm, Active-Comparator Study to Assess the Efficacy and Tolerability of Ofatumumab 20mg SC monthly vs. First Line DMT - physician’s choice in the treatment of newly diagnosed RMS (STHENOS)
CompletedCTIS2023-507431-37-00
Start: 2021-07-23End: 2025-11-04Target: 186Updated: 2025-06-02
DESIRE MS: A prospective randomized non-inferiority trial comparing anti-CD20 maintenance versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
Not yet recruitingCTIS2024-513292-40-00
Target: 250Updated: 2025-04-28
A Study to Learn About the Safety of Diroximel Fumarate (DRF) and Dimethyl Fumarate (DMF) and Their Effects on Relapses in Pediatric Participants With Relapsing Forms of Multiple Sclerosis (RMS)
Not yet recruitingNCT07483632
Start: 2026-11-16End: 2035-06-19Target: 185Updated: 2026-03-19
Unknown Phase
Relationship Between Oral DMT Burden and Adherence in MS
Enrolling by invitationNCT04676204
Start: 2020-09-25End: 2026-07-11Target: 323Updated: 2022-08-31
Study of Diroximel Fumarate in the Real-World Setting
TerminatedNCT04746976
Start: 2021-03-01End: 2023-04-14Updated: 2023-05-26
Exploring Diroximel Fumarate Real-world Experience in Canada and Israel
TerminatedNCT04948606
Start: 2021-12-09End: 2023-04-14Updated: 2023-05-10
Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)
RecruitingNCT05658497
Start: 2023-10-27End: 2032-07-06Target: 908Updated: 2025-08-01
A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies
RecruitingNCT05688436
Start: 2021-09-24End: 2031-01-17Target: 1178Updated: 2025-10-17
A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)
Active, not recruitingNCT05767736
Start: 2024-06-08End: 2032-12-01Target: 10500Updated: 2025-10-16