Diffusing Alpha Radiation Emitters Therapy (DaRT)

DEVICE4 trials

Conditions

Breast CancerBreast CarcinomaHead and Neck Squamous Cell CarcinomaLiver MetastasesMetastatic Head-and-neck Squamous-cell CarcinomaRecurrent Breast CancerSkin CancerSquamous Cell Carcinoma

Unknown Phase

Alpha Radiation Emitters Device for the Treatment of Squamous Cell Carcinoma

CompletedNCT03015883

Alpha Tau Medical LTD.Squamous Cell Carcinoma

Start: 2017-02-22End: 2019-06-25Updated: 2021-01-13

Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC

RecruitingNCT05047094

Alpha Tau Medical LTD.Head and Neck Squamous Cell Carcinoma, Metastatic Head-and-neck Squamous-cell Carcinoma, Skin Cancer

Start: 2021-11-02End: 2027-06-01Target: 48Updated: 2026-04-06

Alpha Radiation Emitters Device (DaRT) for the Treatment of Liver Metastases

RecruitingNCT05829291

Alpha Tau Medical LTD.Liver Metastases

Start: 2023-10-01End: 2027-07-01Target: 10Updated: 2026-06-16

A Study of Diffusing Alpha Radiation Therapy for Patients With Breast Carcinoma in Frail or Elderly Patients.

RecruitingNCT06202118

Alpha Tau Medical LTD.Breast Cancer, Breast Carcinoma, Recurrent Breast Cancer

Start: 2024-02-19End: 2026-06-30Target: 10Updated: 2025-02-07

Cancers2024-06-2410 citations

Quad-shot-immunotherapy: quad-shot radiotherapy with pembrolizumab for advanced/recurrent head and neck cancer

Future Oncology2023-05-185 citations

Initial safety and tumor control results from a phase I prospective trial evaluating a novel alpha-emitting radionuclide for the treatment of locally advanced recurrent squamous cell carcinomas of the skin and head and neck.

Journal of Clinical Oncology2020-05-201 citations

Clinical evidence of abscopal effect in cutaneous squamous cell carcinoma treated with diffusing alpha emitters radiation therapy: a case report.

2019-10-3038 citations

Diffusing Alpha Radiation Emitters Therapy (DaRT)

Sponsors

Conditions

Unknown Phase

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