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Dextromethorphan hydrobromide

DRUG15 trials

Sponsors

NCIC Clinical Trials Group, University of Medicine and Dentistry of New Jersey, Mayo Clinic, Janssen Research & Development, LLC, National Cancer Institute (NCI)

Conditions

Abortion in First TrimesterAdult Solid NeoplasmBreast CancerChronic Myeloproliferative DisordersCoughDiabetic Macular EdemaFatigueHealthy

Phase 1

A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer
CompletedNCT01017939
Janssen Research & Development, LLCProstate Neoplasms
Start: 2010-01-31End: 2012-04-30Updated: 2013-04-12
Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced Solid Tumors
CompletedNCT01218620
National Cancer Institute (NCI)Adult Solid Neoplasm
Start: 2010-09-30End: 2014-12-31Updated: 2014-12-23
Dextromethorphan for Diabetic Macular Edema
CompletedNCT01441102
National Eye Institute (NEI)Diabetic Macular Edema
Start: 2011-08-31End: 2015-12-31Updated: 2020-07-28
Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers
CompletedNCT02182336
Boehringer IngelheimHealthy
Start: 2008-06-30Updated: 2014-07-18
Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers
CompletedNCT02243553
Boehringer IngelheimHealthy
Start: 2006-01-31Updated: 2014-09-18
Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers
CompletedNCT02256813
Boehringer IngelheimHealthy
Start: 2005-09-30Updated: 2014-10-06
A Trial of Dextromethorphan for Treatment of Major Depressive Disorder
CompletedNCT02860962
Medical University of South CarolinaMajor Depressive Disorder
Start: 2016-08-31End: 2017-06-30Updated: 2018-10-25

Phase 2

Dextromethorphan, Amantadine and Glucose Homeostasis in Diabetes Subjects
CompletedNCT01441986
Profil Institut für Stoffwechselforschung GmbHType 2 Diabetes Mellitus
Start: 2011-09-30End: 2012-05-31Updated: 2012-07-12

Phase 3

Treatment for Chronic Pain in Patients With Advanced Cancer
CompletedNCT00003687
NCIC Clinical Trials GroupChronic Myeloproliferative Disorders, Leukemia, Lymphoma +6
Start: 1998-06-11End: 2009-02-10Updated: 2020-04-03
Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion
CompletedNCT03480009
Study Investigator-SponsorAbortion in First Trimester
Start: 2018-07-28End: 2019-06-30Updated: 2020-08-06

Phase 4

Dextromethorphan Pediatric Acute Cough Study
TerminatedNCT02651116
PfizerCough
Start: 2016-02-25End: 2020-03-19Updated: 2021-04-28

Unknown Phase

Dextromethorphan in Treating Patients With Fatigue Caused by Cancer
TerminatedNCT00176540
University of Medicine and Dentistry of New JerseyFatigue, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
Start: 2003-10-31End: 2007-08-31Target: 30Updated: 2011-05-17
Breath Test for Women Receiving Tamoxifen in the Prevention or Treatment of Breast Cancer
TerminatedNCT00873366
Mayo ClinicBreast Cancer
Start: 2009-05-31End: 2015-09-23Updated: 2018-01-23
Efficacy Study of Dextromethorphan to Treat Rheumatoid Arthritis
CompletedNCT02368093
Taichung Veterans General HospitalRheumatoid Arthritis
Start: 2010-01-31End: 2012-09-30Updated: 2015-03-31
Dextromethorphan for Treatment of Postoperative Pain
RecruitingNCT05278494
Nathanael HeckmannPost-operative Pain
Start: 2022-09-15End: 2026-12-31Target: 160Updated: 2026-03-27

Related Papers

Supporting respiratory epithelia and lowering inflammation to effectively treat common cold symptoms: A randomized controlled trial
PLoS ONE2024-11-27
A double-blinded, placebo-controlled, randomized study to evaluate the efficacy of perioperative dextromethorphan compared to placebo for the treatment of postoperative pain: a study protocol.
2023-03-293 citations