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Dexamethasone Tablets BP 2.0mg

DRUG15 trials

Sponsors

Janssen - Cilag International, Glaxosmithkline Research & Development Limited, University Of Oxford, Pfizer Inc., Celgene Corp.

Conditions

Acute Lymphoblastic Leukemia (ALL)Multiple MyelomaMultiple myelomaMultiple myeloma (MM) with at least 2 prior therapies including an immunomodulatory (IMiD) compound and a proteasome inhibitor (PI) and demonstrated disease progression on or within 60 days of completion of the last therapy.PneumoniaRelapsed and Lenalidomide-Refractory Multiple MyelomaRelapsed or Refractory Multiple MyelomaRelapsed or Refractory Myeloma

Phase 1

Phase 2

Phase 3

RANDOMISED EVALUATION OF COVID-19 THERAPY (RECOVERY)
RecruitingCTIS2023-507441-29-00
University Of OxfordPneumonia
Start: 2024-02-29Target: 1590Updated: 2025-11-10
A Phase 3 Randomized Study Comparing Talquetamab in Combination with Pomalidomide (Tal-P), Talquetamab in Combination with Teclistamab (Tal-Tec), and Investigator’s Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pomalidomide, Bortezomib, and Dexamethasone (PVd) in Participants with Relapsed or Refractory Myeloma who Have Received 1 to 4 Prior Lines of Therapy Including an Anti-CD38 Antibody and Lenalidomide
Active, not recruitingCTIS2022-502446-27-00
Janssen - Cilag InternationalRelapsed or Refractory Myeloma
Start: 2024-02-26Target: 453Updated: 2026-01-13
A Phase 3 Randomized Study Comparing JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA, versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Subjects with Relapsed and Lenalidomide-Refractory Multiple Myeloma CARTITUDE-4
Active, not recruitingCTIS2023-506588-32-00
Janssen - Cilag InternationalRelapsed and Lenalidomide-Refractory Multiple Myeloma
Start: 2020-06-12Target: 233Updated: 2025-09-03
A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA versus Bortezomib, Lenalidomide, and Dexamethasone (VRd) followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants with Newly Diagnosed Multiple Myeloma for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy.
Active, not recruitingCTIS2023-505850-16-00
Janssen - Cilag InternationalMultiple Myeloma
Start: 2021-08-05Target: 371Updated: 2026-01-19
DREAMM 7: A Multicenter, Open-Label, Randomized Phase III Study to Evaluate the Efficacy and Safety of the Combination of Belantamab Mafodotin, Bortezomib, and Dexamethasone (B-Vd) Compared with the Combination of Daratumumab, Bortezomib and Dexamethasone (D-Vd) in Participants with Relapsed/Refractory Multiple Myeloma
Active, not recruitingCTIS2023-510537-28-00
Glaxosmithkline Research & Development LimitedMultiple Myeloma
Start: 2020-05-15Target: 203Updated: 2025-10-30
A Phase 3, Multicenter, Randomized, Open-label Study to Compare the Efficacy and Safety of bb2121 Versus Standard Regimens in Subjects with Relapsed and Refractory Multiple Myeloma (RRMM) (KarMMa-3)
Active, not recruitingCTIS2023-509848-10-00
Celgene Corp.Multiple myeloma (MM) with at least 2 prior therapies including an immunomodulatory (IMiD) compound and a proteasome inhibitor (PI) and demonstrated disease progression on or within 60 days of completion of the last therapy.
Start: 2019-06-12Target: 138Updated: 2025-11-28
A Phase 3 Randomized Study Comparing Talquetamab SC in Combination With Daratumumab SC and Pomalidomide (Tal-DP) or Talquetamab SC in Combination With Daratumumab SC (Tal-D) Versus Daratumumab SC, Pomalidomide and Dexamethasone (DPd), in Participants With Relapsed or Refractory Multiple Myeloma who Have Received at Least 1 Prior Line of Therapy
Active, not recruitingCTIS2023-503467-41-00
Janssen - Cilag InternationalRelapsed or Refractory Multiple Myeloma
Start: 2022-10-12Target: 310Updated: 2026-01-27
A Phase 3 Randomized Study Comparing Teclistamab Monotherapy versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants with Relapsed or Refractory Multiple Myeloma who have Received 1 to 3 Prior Lines of Therapy, Including an Anti-CD38 Monoclonal Antibody and Lenalidomide
Active, not recruitingCTIS2023-503444-13-00
Janssen - Cilag InternationalRelapsed/refractory multiple myeloma
Start: 2023-03-29Target: 291Updated: 2025-10-23
A Phase III, Multicenter, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination with Pomalidomide and Dexamethasone (B-Pd) versus Pomalidomide plus Bortezomib and Dexamethasone (PVd) in Participants with Relapsed/Refractory Multiple Myeloma (DREAMM 8)
Active, not recruitingCTIS2023-506877-37-00
Glaxosmithkline Research & Development LimitedRelapsed/Refractory Multiple Myeloma
Start: 2020-09-28Target: 148Updated: 2025-12-15
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination with Daratumumab SC and Lenalidomide (Tal-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy
RecruitingCTIS2023-503442-30-00
Janssen - Cilag InternationalMultiple Myeloma
Start: 2022-10-14Target: 563Updated: 2025-09-02
A Phase 3, randomized, open-label study of belantamab mafodotin administered in combination with lenalidomide and dexamethasone versus daratumumab, lenalidomide, and dexamethasone in participants with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation (TI-NDMM)-DREAMM-10
RecruitingCTIS2024-516030-35-00
Glaxosmithkline Research & Development LimitedMultiple myeloma
Start: 2025-04-30Target: 225Updated: 2025-10-16