Dexamethasone Tablets BP 2.0mg
Sponsors
Janssen - Cilag International, Glaxosmithkline Research & Development Limited, University Of Oxford, Pfizer Inc., Celgene Corp.
Conditions
Acute Lymphoblastic Leukemia (ALL)Multiple MyelomaMultiple myelomaMultiple myeloma (MM) with at least 2 prior therapies including an immunomodulatory (IMiD) compound and a proteasome inhibitor (PI) and demonstrated disease progression on or within 60 days of completion of the last therapy.PneumoniaRelapsed and Lenalidomide-Refractory Multiple MyelomaRelapsed or Refractory Multiple MyelomaRelapsed or Refractory Myeloma
Phase 1
Phase 2
A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA in Subjects with Multiple Myeloma
CARTITUDE-2
Active, not recruitingCTIS2023-506587-13-00
Start: 2020-01-30Target: 56Updated: 2025-09-02
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC (Tec-Dara) versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants with Relapsed or Refractory Multiple Myeloma
Active, not recruitingCTIS2023-503441-55-00
Start: 2021-10-14Target: 310Updated: 2025-09-27
B1931036 - A prospective, randomized, open-label phase 2 study to evaluate the superiority of Inotuzumab Ozogamicin monotherapy versus ALLR3 for induction treatment of childhood high risk first relapse B-cell precursor Acute Lymphoblastic Leukaemia
RecruitingCTIS2023-509810-13-00
Start: 2023-05-13Target: 94Updated: 2025-10-27
Phase 3
RANDOMISED EVALUATION OF COVID-19 THERAPY (RECOVERY)
RecruitingCTIS2023-507441-29-00
Start: 2024-02-29Target: 1590Updated: 2025-11-10
A Phase 3 Randomized Study Comparing Talquetamab in Combination with Pomalidomide (Tal-P), Talquetamab in Combination with Teclistamab (Tal-Tec), and Investigator’s Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pomalidomide, Bortezomib, and Dexamethasone (PVd) in Participants with Relapsed or Refractory Myeloma who Have Received 1 to 4 Prior Lines of Therapy Including an Anti-CD38 Antibody and Lenalidomide
Active, not recruitingCTIS2022-502446-27-00
Start: 2024-02-26Target: 453Updated: 2026-01-13
A Phase 3 Randomized Study Comparing JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA, versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Subjects with Relapsed and Lenalidomide-Refractory Multiple Myeloma
CARTITUDE-4
Active, not recruitingCTIS2023-506588-32-00
Start: 2020-06-12Target: 233Updated: 2025-09-03
A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA versus Bortezomib, Lenalidomide, and Dexamethasone (VRd) followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants with Newly Diagnosed Multiple Myeloma for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy.
Active, not recruitingCTIS2023-505850-16-00
Start: 2021-08-05Target: 371Updated: 2026-01-19
DREAMM 7: A Multicenter, Open-Label, Randomized Phase III Study to Evaluate the Efficacy and Safety of the Combination of Belantamab Mafodotin, Bortezomib, and Dexamethasone (B-Vd) Compared with the Combination of Daratumumab, Bortezomib and Dexamethasone (D-Vd) in Participants with Relapsed/Refractory Multiple Myeloma
Active, not recruitingCTIS2023-510537-28-00
Start: 2020-05-15Target: 203Updated: 2025-10-30
A Phase 3, Multicenter, Randomized, Open-label Study to Compare the Efficacy and Safety of bb2121 Versus Standard Regimens in Subjects with Relapsed and Refractory Multiple Myeloma
(RRMM) (KarMMa-3)
Active, not recruitingCTIS2023-509848-10-00
Start: 2019-06-12Target: 138Updated: 2025-11-28
A Phase 3 Randomized Study Comparing Talquetamab SC in Combination With Daratumumab SC and Pomalidomide (Tal-DP) or Talquetamab SC in Combination With Daratumumab SC (Tal-D) Versus Daratumumab SC, Pomalidomide and Dexamethasone (DPd), in Participants With Relapsed or Refractory Multiple Myeloma who Have Received at Least 1 Prior Line of Therapy
Active, not recruitingCTIS2023-503467-41-00
Start: 2022-10-12Target: 310Updated: 2026-01-27
A Phase 3 Randomized Study Comparing Teclistamab Monotherapy versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants with Relapsed or Refractory Multiple Myeloma who have Received 1 to 3 Prior Lines of Therapy, Including an Anti-CD38 Monoclonal Antibody and Lenalidomide
Active, not recruitingCTIS2023-503444-13-00
Start: 2023-03-29Target: 291Updated: 2025-10-23
A Phase III, Multicenter, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination with Pomalidomide and Dexamethasone (B-Pd) versus Pomalidomide plus Bortezomib and Dexamethasone (PVd) in Participants with Relapsed/Refractory Multiple Myeloma (DREAMM 8)
Active, not recruitingCTIS2023-506877-37-00
Start: 2020-09-28Target: 148Updated: 2025-12-15
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination with Daratumumab SC and Lenalidomide (Tal-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy
RecruitingCTIS2023-503442-30-00
Start: 2022-10-14Target: 563Updated: 2025-09-02
A Phase 3, randomized, open-label study of belantamab mafodotin administered in combination with lenalidomide and dexamethasone versus daratumumab, lenalidomide, and dexamethasone in participants with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation (TI-NDMM)-DREAMM-10
RecruitingCTIS2024-516030-35-00
Start: 2025-04-30Target: 225Updated: 2025-10-16